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About This Item
经验公式（希尔记法）:
C14H9ClF3NO2
CAS号:
分子量:
315.67
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77
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品質等級
化驗
≥98% (HPLC)
形狀
powder
光學活性
[α]/D -90 to -100°, c = 1 in methanol
顏色
white to beige
溶解度
DMSO: 15 mg/mL, clear
儲存溫度
−20°C
SMILES 字串
ClC1=CC=C2C([C@@](C#CC3CC3)(C(F)(F)F)OC(N2)=O)=C1
InChI
1S/C14H9ClF3NO2/c15-9-3-4-11-10(7-9)13(14(16,17)18,21-12(20)19-11)6-5-8-1-2-8/h3-4,7-8H,1-2H2,(H,19,20)/t13-/m0/s1
InChI 密鑰
XPOQHMRABVBWPR-ZDUSSCGKSA-N
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一般說明
具有Sustiva™商品名的依法韦仑是一种含有苯和恶嗪-2-酮发色团的多环芳烃。
應用
依法韦仑已用于：
- 评估其抗猪内源性逆转录病毒（PERV）活性
- 细胞毒性检测
- 通过结合时间密度泛函理论（TD-DFT）和光谱计算的方法，研究依法韦仑的溶质-溶剂效应
生化／生理作用
依法韦仑是一种非核苷类逆转录酶抑制剂（NNRTI）。它是一种抗HIV药物，常用于AIDs治疗的联合疗法。它是用于治疗人类免疫缺陷病毒（HIV）1型的高效抗逆转录病毒疗法（HAART）的一部分。
特點和優勢
这种化合物是 ADME 毒性研究的特色产品。点击此处发现更多特色 ADME 毒性产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。
法律資訊
Sustiva is a trademark of E. I. du Pont de Nemours and Company
訊號詞
Danger
危險分類
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 1B
儲存類別代碼
6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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