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Merck

V0033000

丙戊酸

European Pharmacopoeia (EP) Reference Standard

别名:

2-丙基戊酸, 丙戊酸

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About This Item

线性分子式:
(CH3CH2CH2)2CHCO2H
CAS号:
分子量:
144.21
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

pharmaceutical primary standard

agency

EP Reference Standard

API 家族

valproic acid

製造商/商標名

EDQM

折射率

n20/D 1.425 (lit.)

bp

220 °C (lit.)

密度

0.9 g/mL at 25 °C (lit.)

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

2-8°C

SMILES 字串

CCCC(C(O)=O)CCC

InChI

1S/C8H16O2/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H,9,10)

InChI 密鑰

NIJJYAXOARWZEE-UHFFFAOYSA-N

基因資訊

human ... ALDH5A1(7915)

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一般說明

本品按现行药典规定交付。所有为支持本产品而提供的信息,包括SDS和任何产品信息单均由药典颁发机构制定并发布。如需进一步信息和支持,请访问现行药典网站。

應用

丙戊酸EP参考标准品的预期用途是欧洲药典规定的实验室测试。

生化/生理作用

抗惊厥药,同时还具有双相障碍症情绪稳定剂的功效

包裝

本品按照现行药典要求提供。有关当前单位数量,请见EDQM 参考目录

其他說明

可能适用相应的销售限制。

訊號詞

Danger

危險分類

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1A - Skin Irrit. 2

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

231.8 °F - closed cup

閃點(°C)

111 °C - closed cup


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Some antiepileptic drugs but not others are useful in clinical practice for the prophylaxis of migraine. This might be explained by the variety of actions of these drugs in the central nervous system. The present review is part of an
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Neuroscience and biobehavioral reviews, 36(8), 1848-1856 (2012-06-02)
Neuropsychiatric medications that directly alter the epigenome, such as valproic acid, can under certain conditions reactivate critical developmental periods and thus impact adult neuroconnectivity. In animal models valproic acid was shown to inhibit the process of postnatal myelination and to
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Valproic acid (VPA) is both an anti-convulsant and a mood stabilizer. Clinical studies over the past 40 years have shown that exposure to VPA in utero is associated with birth defects, cognitive deficits, and increased risk of autism. Two recent
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Clinical biochemistry, 46(15), 1323-1338 (2013-06-25)
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