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品質等級
化驗
≥98% (HPLC)
形狀
powder
光學活性
[α]/D -20 to -26°, c = 0.5 in 1 M HCl
顏色
white to beige
溶解度
H2O: 2 mg/mL, clear (warmed)
儲存溫度
−20°C
SMILES 字串
OP(CO[C@H](C)CN1C2=NC=NC(N)=C2N=C1)(O)=O
InChI
1S/C9H14N5O4P/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17)/t6-/m1/s1
InChI 密鑰
SGOIRFVFHAKUTI-ZCFIWIBFSA-N
生化/生理作用
替诺福韦是一种核苷酸类似物逆转录酶抑制剂(nRTI),可导致DNA转录过早终止。替诺福韦是一种用于HIV治疗和预防的抗逆转录病毒药物。
替诺福韦的口服生物利用度较低。因此,它可以作为称为替诺福韦地索普西富马酸盐的前药。一旦摄入,替诺福韦地索普西富马酸盐可被水解成替诺福韦并被磷酸化。然后将其掺入病毒DNA中,导致链终止。替诺福韦对乙型肝炎病毒也有效。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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