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Merck

SMB00705

Sigma-Aldrich

芝麻素

≥98% (HPLC)

别名:

崖椒醇

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About This Item

经验公式(希尔记法):
C20H18O6
CAS号:
分子量:
354.35
MDL號碼:
分類程式碼代碼:
12352205
NACRES:
NA.25

品質等級

化驗

≥98% (HPLC)

形狀

powder

溶解度

DMSO: 10 mg/mL

應用

metabolomics
vitamins, nutraceuticals, and natural products

儲存溫度

−20°C

SMILES 字串

C1Oc2ccc(cc2O1)[C@H]3OC[C@H]4[C@@H]3CO[C@@H]4c5ccc6OCOc6c5

InChI

1S/C20H18O6/c1-3-15-17(25-9-23-15)5-11(1)19-13-7-22-20(14(13)8-21-19)12-2-4-16-18(6-12)26-10-24-16/h1-6,13-14,19-20H,7-10H2/t13-,14-,19+,20+/m0/s1

InChI 密鑰

PEYUIKBAABKQKQ-AFHBHXEDSA-N

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一般說明

芝麻素是从芝麻或芝麻籽和芝麻油中提取的最丰富的木脂素。

應用

芝麻素已用作参考标准品以研究芝麻中细胞色素P450酶芝麻素合酶在将松香素转化为芝麻素的活性。

生化/生理作用

芝麻素具有多种健康益处,包括降胆固醇、降压、抗癌、抗衰老、免疫调节、降血糖、抗血栓、保肝和抗氧化活性等。它还被证明可以与维生素E协同抗脂质过氧化。研究发现,芝麻素在肝脏中被代谢成几种儿茶酚形式。这些儿茶酚具有很强的清除超氧自由基的能力。
非竞争性δ 5-去饱和酶抑制剂。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Skin Sens. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Yun-Ping Lim et al.
Evidence-based complementary and alternative medicine : eCAM, 2012, 242810-242810 (2012-05-31)
Inconsistent expression and regulation of drug-metabolizing enzymes (DMEs) are common causes of adverse drug effects in some drugs with a narrow therapeutic index (TI). An important cytochrome, cytochrome P450 3A4 (CYP3A4), is predominantly regulated by a nuclear receptor, pregnane X
Colonoscope constriction and laser safety interlock problems investigated.
Today's OR nurse, 14(3), 48-48 (1992-03-01)
Mitsuo Namiki
Critical reviews in food science and nutrition, 47(7), 651-673 (2007-10-19)
The results of recent food chemical and nutraceutical studies on the traditionally well-known health value of sesame are described, including some aspects of the utilization of sesame. The highly antioxidative activity of sesame oil was clarified and found to involve
Sarah Dalibalta et al.
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 28(10), 1276-1289 (2020-11-03)
Sesamin, a major lignin isolated from sesame (Sesamum indicum) seeds and sesame oil, is known to possess antioxidant and anti-inflammatory properties. Several studies have revealed that oxidative stress and inflammation play a major role in a variety of cardiovascular diseases
Kaori Yasuda et al.
Expert opinion on drug metabolism & toxicology, 8(1), 93-102 (2011-11-22)
Sesamin is a major lignan found in sesame and is known to have various biological effects. Some of these biological effects occur following its metabolic conversion to corresponding catechols and, therefore, the study of sesamin metabolism is quite important. There

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