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Merck

SMB00701

Sigma-Aldrich

芝麻林素

≥97%, from Sesamum indicum (sesame)

别名:

5-[(1S,3aR,4R,6aR)-4-(1,3- 苯并二唑-5-烷氧基)四羟基-1H,3H-furo[3,4-c]呋喃-1-基]-1,3-苯并二恶唑

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About This Item

经验公式(希尔记法):
C20H18O7
CAS号:
分子量:
370.35
分類程式碼代碼:
12352205
NACRES:
NA.25

生物源

Sesamum indicum (sesame)

品質等級

化驗

≥97%

形狀

powder

溶解度

DMSO: 10 mg/mL

應用

metabolomics
vitamins, nutraceuticals, and natural products

儲存溫度

−20°C

SMILES 字串

[H][C@@]12[C@@H](C(C=C3)=CC4=C3OCO4)OC[C@]1([H])[C@@H](OC5=CC6=C(C=C5)OCO6)OC2

InChI

1S/C20H18O7/c1-3-15-17(25-9-23-15)5-11(1)19-13-7-22-20(14(13)8-21-19)27-12-2-4-16-18(6-12)26-10-24-16/h1-6,13-14,19-20H,7-10H2/t13-,14-,19+,20+/m0/s1

InChI 密鑰

ZZMNWJVJUKMZJY-AFHBHXEDSA-N

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一般說明

芝麻素是从芝麻中提取的呋喃木脂素。它在水中的溶解度很小。芝麻素的化学结构包括两种苯丙素,它们的丙基侧连接到中心碳上。在许多其他芝麻品种中也有报道。

生化/生理作用

它还具有抗菌、抗黑色素生成和神经保护作用。
据报道,芝麻素具有有益的生理特性,如抗氧化、抗突变、抗衰老和抗炎活性。 对大鼠肝、肾的脂质过氧化也有抑制作用。芝麻素通过增加Burkitts淋巴瘤细胞上NKG2D配体的表达,增强NK细胞的裂解活性,在癌症治疗中具有潜在的免疫治疗价值。 此外,研究表明,芝麻素可抑制β-分泌酶,通过日常食用对预防痴呆具有重要作用。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

防範說明

危險分類

Skin Sens. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Jeong Hwa Kim et al.
International immunopharmacology, 28(2), 977-984 (2015-08-25)
Sesamolin and sesamin are representative lignans found in sesame seed. The present study was designed to demonstrate the anti-cancer activity of sesamolin achieved by increasing the expression level of NKG2D ligands on Raji cells, which are derived from Burkitt's lymphoma.
Reny Rosalina et al.
Molecules (Basel, Switzerland), 26(19) (2021-10-14)
Sesame seeds are rich in lignan content and have been well-known for their health benefits. Unlike the other sesame lignan compounds (i.e., sesamin and sesamol), the study of the pharmacological activity of sesamolin has not been explored widely. This review
M H Kang et al.
The Journal of nutrition, 128(6), 1018-1022 (1998-06-18)
Although the sesame lignans, sesaminol and sesamolinol, have been shown to possess antioxidative activity, less is known about the metabolism and antioxidative properties of sesamolin, a major constituent of sesame oil. To determine the ability of sesamolin to act as
T Lind et al.
Acta orthopaedica Belgica, 58(1), 81-83 (1992-01-01)
The intra-articular pressures in the glenohumeral joint in different positions were measured in 12 cadaveric shoulders. The lowest pressure was found in abduction combined with traction. A significant rise in pressure was seen in positions combining flexion or abduction with
β-secretase inhibitors from sesame seeds and turmeric rhizomes
Murata K, et al.
Planta Medica, 82, S1-S381 (2016)

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