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Merck

F7759

Sigma-Aldrich

Anti-Horse IgG (whole molecule)−FITC antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

别名:

Rabbit Anti-Horse IgG (whole molecule)−Fluorescein isothiocyanate

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.46

生物源

rabbit

品質等級

共軛

FITC conjugate

抗體表格

affinity isolated antibody

抗體產品種類

secondary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

儲存條件

protect from light

技術

direct immunofluorescence: suitable

儲存溫度

−20°C

目標翻譯後修改

unmodified

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一般說明

An immunoglobulin has two heavy chains and two light chains connected by disulfide bond. It is a glycoprotein. IgG is a major class of immunoglobulin. Horse IgG has different subclasses, IgG2a, IgG2b, IgG2c, IgG1 and IgG(T). Compared to other IgG molecules, IgG(T) has more carbohydrate content. In healthy individuals, total IgG is dispersed equally between circulating plasma and interstitial fluids.
Horse IgG is a plasma B cell derived antibody isotype defined by its heavy chain. IgG is the most abundant antibody isotype found in horse serum. IgG crosses the placental barrier, is a complement activator and binds to the Fc-receptors on phagocytic cells. The level of IgG may vary with the status of disease or infection.

特異性

Anti-horse IgG (whole molecule)-FITC antibody is specific for horse IgG subclasses.

免疫原

Purified horse IgG

應用

Anti-Horse IgG (whole molecule) FITC antibody produced in rabbit has been used in indirect fluorescent antibody test. It has also been used as a secondary antibody to confirm equine arteritis virus (EAV).
Rabbit polyclonal anti-Horse IgG (whole molecule)−FITC antibody may be used to detect and quantitate the level of IgG in horse serum and biological fluids by fluorescent techniques. It may also be used as a secondary antibody in assays that use horse IgG as the primary antibody.

生化/生理作用

IgG antibody subtype is the most abundant serum immunoglobulin of the immune system. It is secreted by B- cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to the fetus through the placenta that is vital for immune defense of the neonate against infections.
Immunoglobulin G (IgG) participates in hypersensitivity type II and type III. It mainly helps in immune defense.

外觀

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide

儲存和穩定性

For continuous use, store at 2-8 °C for up to one month. For extended storage, the solution may be frozen in working aliquots. Repeated freezing and thawing or storage in "frost-free" freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Manuela Scarpulla et al.
Annals of the New York Academy of Sciences, 990, 259-263 (2003-07-16)
The authors review equine granulocytic ehrlichiosis (EGE) in Italy from 1996 to 2002. In 1996, the first case of EGE has been observed in a horse affected with specific symptomatology (fever, lethargy, anorexia, limb edema, thrombocytopenia, and petechiae). In 1997
A 34-year retrospective study of equine viral abortion in Poland
Bazanow BA, et al.
Polish Journal of Veterinary Sciences, 17(4), 607-612 (2014)
Advances in Immunology (1964)
Factors associated with the distribution of natural Toxoplasma gondii infection among equids in Northeastern Brazil
Munhoz AD, et al.
Revista Brasileira de Parasitologia veterinaria = Brazilian Journal of Veterinary Parasitology : Org?o Oficial do Colegio Brasileiro de Parasitologia Veterinaria, 28(2), 283-290 (2019)
Molecular Genetics of Immunoglobulin (1987)

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