跳转至内容
Merck

D0627

Sigma-Aldrich

N6,2′-O-二丁酰基腺苷 3′,5′-环单磷酸 钠盐

≥96% (HPLC), powder

别名:

二丁酰 cAMP 钠盐, 二丁酰环磷腺苷 钠盐, 布拉地新 钠盐

登录查看公司和协议定价


About This Item

线性分子式:
C18H23N5O8PNa
CAS号:
分子量:
491.37
EC號碼:
MDL號碼:
分類程式碼代碼:
41106305
PubChem物質ID:
NACRES:
NA.51

生物源

synthetic (organic)

品質等級

化驗

≥96% (HPLC)

形狀

powder

雜質

≤0.5% Cyclic AMP
≤3% monobutyryl derivatives

顏色

off-white

溶解度

H2O: 100 mg/mL

儲存溫度

−20°C

SMILES 字串

[Na+].CCCC(=O)Nc1ncnc2n(cnc12)[C@@H]3O[C@@H]4COP([O-])(=O)O[C@H]4[C@H]3OC(=O)CCC

InChI

1S/C18H24N5O8P.Na/c1-3-5-11(24)22-16-13-17(20-8-19-16)23(9-21-13)18-15(30-12(25)6-4-2)14-10(29-18)7-28-32(26,27)31-14;/h8-10,14-15,18H,3-7H2,1-2H3,(H,26,27)(H,19,20,22,24);/q;+1/p-1/t10-,14-,15-,18-;/m1./s1

InChI 密鑰

KRBZRVBLIUDQNG-JBVYASIDSA-M

正在寻找类似产品? 访问 产品对比指南

應用

二丁酰基CAMP是一种可激活CAMP 依赖性蛋白激酶 (PKA)或CAMP/PKA信号传导途径的细胞可渗透型CAMP类似物。 二丁酰基CAMP可用作施万细胞等细胞的形态学分化诱导剂和细胞信号调节剂。 二丁酰基cAMP可用于多种分化研究,如神经元分化/神经分化。

生化/生理作用

细胞通透性 cAMP 类似物,可激活 cAMP 依赖性蛋白激酶 (PKA)。

注意

在 pH 8.5 下会失去 2′-O-丁酰基

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Junji Yamauchi et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 31(35), 12579-12592 (2011-09-02)
In development of the peripheral nervous system, Schwann cells proliferate, migrate, and ultimately differentiate to form myelin sheath. In all of the myelination stages, Schwann cells continuously undergo morphological changes; however, little is known about their underlying molecular mechanisms. We
Witold Korytowski et al.
FEBS letters, 588(1), 65-70 (2013-11-26)
StAR family proteins in vascular macrophages participate in reverse cholesterol transport (RCT). We hypothesize that under pathophysiological oxidative stress, StARs will transport not only cholesterol to macrophage mitochondria, but also pro-oxidant cholesterol hydroperoxides (7-OOHs), thereby impairing early-stage RCT. Upon stimulation
Asad Jan et al.
Acta neuropathologica communications, 6(1), 54-54 (2018-07-03)
Parkinson disease (PD) is the second most common neurodegenerative disorder and the leading neurodegenerative cause of motor disability. Pathologic accumulation of aggregated alpha synuclein (AS) protein in brain, and imbalance in the nigrostriatal system due to the loss of dopaminergic
Steven L Coon et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(33), 13319-13324 (2012-08-07)
Long noncoding RNAs (lncRNAs) play a broad range of biological roles, including regulation of expression of genes and chromosomes. Here, we present evidence that lncRNAs are involved in vertebrate circadian biology. Differential night/day expression of 112 lncRNAs (0.3 to >50
Ana Borrajo et al.
Neuropharmacology, 85, 1-8 (2014-06-01)
Several recent studies have shown that activation of the RhoA/Rho-associated kinase (ROCK) pathway is involved in the MPTP-induced dopaminergic cell degeneration and possibly in Parkinson's disease. ROCK inhibitors have been suggested as candidate neuroprotective drugs for Parkinson's disease. However, the

实验方案

Step-by-step culture protocols for neural stem cell culture including NSC isolation, expansion, differentiation and characterization.

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门