推荐产品
生物源
Coleus forskohlii
描述
for activation of T cells
產品線
BioReagent
化驗
≥98% (HPLC)
形狀
powder
分子量
410.50 g/mol
顏色
white to off-white
溶解度
ethanol: soluble
適合性
suitable for inhibits interleukin 2 (IL-2) production in Jurkat cells
儲存溫度
room temp
SMILES 字串
CC(=O)O[C@H]1[C@@H](O)[C@H]2C(C)(C)CC[C@H](O)[C@]2(C)[C@@]3(O)C(=O)C[C@@](C)(O[C@]13C)C=C
InChI
1S/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(26)17(28-12(2)23)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3/t13-,15-,16-,17-,19-,20-,21+,22-/m0/s1
InChI 密鑰
OHCQJHSOBUTRHG-KGGHGJDLSA-N
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一般說明
毛喉素是从Coleus forskohlii分离提取的细胞渗透双萜。
生化／生理作用
具有抗高血压、正性变力作用和腺苷酸环化酶活化特性的细胞通透性二萜类化合物。它的许多生物学作用是由于其对腺苷酸环化酶的激活以及由此而导致的细胞内cAMP浓度增加。毛喉素可影响钙电流并抑制MAP激酶。
訊號詞
Warning
危險聲明
危險分類
Acute Tox. 4 Dermal
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
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Extensive work has shown that activation of the cAMP-dependent protein kinase A (PKA) is crucial for long-term depression (LTD) of synaptic transmission in the hippocampus, a phenomenon that is thought to be involved in memory formation. Here we studied the
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