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品質等級
化驗
≥97% (HPLC)
形狀
powder
顏色
off-white
溶解度
H2O: 100 mg/mL
儲存溫度
−20°C
SMILES 字串
[Na+].Nc1ncnc2n([C@@H]3O[C@@H]4COP([O-])(=O)O[C@H]4[C@H]3O)c(Br)nc12
InChI
1S/C10H11BrN5O6P.Na/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-5(17)6-3(21-9)1-20-23(18,19)22-6;/h2-3,5-6,9,17H,1H2,(H,18,19)(H2,12,13,14);/q;+1/p-1/t3-,5-,6-,9-;/m1./s1
InChI 密鑰
DMRMZQATXPQOTP-GWTDSMLYSA-M
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相关类别
一般說明
8-溴腺苷3′,5′-环单磷酸是溴化环单核苷酸。
應用
8-溴腺苷3′,5′-环单磷酸钠盐用于:
- 研究其对牛黄体中期细胞fas和caspase-3 mRNA表达以及P4产量的影响
- 用于治疗绒毛膜癌BeWo细胞系,研究其对细胞活力,细胞凋亡和细胞核形态变化的影响
- 在灌注介质中刺激头肾
生化/生理作用
比 cAMP 更抗磷酸二酯酶水解的细胞通透性 cAMP 类似物。激活培养细胞的蛋白激酶 A、抑制生长、减少增殖、增加分化并诱导凋亡。
特點和優勢
该化合物是环核苷酸研究的特色产品。点击此处查看更多特色环核苷酸产品。了解更多有关用于其他研究领域的生物活性小分子的信息,请访问 sigma.com/discover-bsm。
其他說明
膜渗透性 cAMP 类似物。
注意
对光和水分敏感。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
PloS one, 8(1), e54336-e54336 (2013-01-26)
Human implantation involves extensive tissue remodeling at the fetal-maternal interface. It is becoming increasingly evident that not only trophoblast, but also decidualizing endometrial stromal cells are inherently motile and invasive, and likely contribute to the highly dynamic processes at the
Effects of corticotrophin releasing hormone (CRH) on cell viability and differentiation in the human BeWo choriocarcinoma cell line: a potential syncytialisation inducer distinct from cyclic adenosine monophosphate (cAMP)
Reproductive Biology and Endocrinology, 11(1), 30-30 (2013)
Corticotropin-releasing factor (CRF) and CRF-binding protein expression in and release from the head kidney of common carp: evolutionary conservation of the adrenal CRF system
The Journal of Endocrinology, 193(3), 349-357 (2007)
Possible roles of intracellular cyclic AMP, protein kinase C and calcium ion in the apoptotic signaling pathway in bovine luteal cells}
Journal of Reproduction and Development, 52(4), 517-522 (2006)
Molecular pain, 3, 22-22 (2007-08-19)
Prostaglandin E2 (PGE2) is a well-known inflammatory mediator that enhances the excitability of DRG neurons. Homomeric P2X3 and heteromeric P2X2/3 receptors are abundantly expressed in dorsal root ganglia (DRG) neurons and participate in the transmission of nociceptive signals. The interaction
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