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應用
ββ-氯-L-丙氨酸盐酸盐已用于:
- 作为底物,用于研究酪氨酸酚裂解酶稳态动力学
- 研究Ly-1淋巴细胞中的丝氨酸棕榈酰转移酶抑制和细胞毒性
- 在小麦胚无细胞蛋白合成系统中作为丙氨酸转氨酶抑制剂
生化/生理作用
ββ-氯-L-丙氨酸盐酸盐是丙氨酸氨基转移酶(ALAT)抑制剂。抑制ALAT可导致肺癌进展抑制。
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
Serine 51 residue of Citrobacter freundii tyrosine phenol-lyase assists in C-alpha-proton abstraction and transfer in the reaction with substrate
Biochimie, 147(1), 63-69 (2018)
Oxytetracycline have the therapeutic efficiency in CD133+ HCC population through suppression CD133 expression by decreasing of protein stability of CD133
Scientific Reports, 8(1), 16100-16100 (2018)
Specificity of inhibitors of serine palmitoyltransferase (SPT), a key enzyme in sphingolipid biosynthesis, in intact cells: a novel evaluation system using an SPT-defective mammalian cell mutant
Biochemical Pharmacology, 59(10), 1211-1216 (2000)
A novel way of amino acid-specific assignment in 1 H-15 N HSQC spectra with a wheat germ cell-free protein synthesis system
Journal of Biomolecular Nmr, 30(1), 37-45 (2004)
Inhibition of alanine aminotransferase (ALAT) in silico and in vivo promotes mitochondrial metabolism to impair malignant growth
The Journal of Biological Chemistry, jbc-M110 (2011)
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