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品質等級
化驗
≥98% (HPLC)
形狀
powder
顏色
white to beige
溶解度
DMSO: 5 mg/mL, clear
儲存溫度
2-8°C
SMILES 字串
CCCCCCCCC1OC(=O)C(=C)C1C(O)=O
InChI
1S/C14H22O4/c1-3-4-5-6-7-8-9-11-12(13(15)16)10(2)14(17)18-11/h11-12H,2-9H2,1H3,(H,15,16)
InChI 密鑰
VCWLZDVWHQVAJU-UHFFFAOYSA-N
應用
C75用于:
- 作为脂肪酸合酶(FASN)抑制剂,测试其相较于二甲双胍,对FASN的直接抑制作用以及减弱乳腺球形成的能力
- 作为抑制神经胶质瘤干细胞(GSC)中脂肪酸合成的药理抑制剂
- 作为FAS 抑制剂 对Chang细胞进行预处理,以抑制脂肪生成并逆转过氧化氢诱导的衰老
生化/生理作用
C75有助于提高电离辐射的抗癌能力。
C75是一种新型、有效的脂肪酸合成酶(FAS)合成抑制剂,可用作研究代谢紊乱和癌症中脂肪酸合成的工具。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
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There are various ways that priming can occur in nucleic acid amplification reactions. While most reactions rely on a primer to initiate amplification, a mechanism for DNA amplification has been developed in which hairpin sequences at the 3' terminus of
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Posttranscriptional modifications are critical for structure and function of tRNAs. Wybutosine (yW) and its derivatives are hyper-modified guanosines found at the position 37 of eukaryotic and archaeal tRNA(Phe). TYW2 is an enzyme that catalyzes α-amino-α-carboxypropyl transfer activity at the third
Nucleic acids research, 45(22), 12974-12986 (2017-10-27)
Post-transcriptional modifications of ribosomal RNAs (rRNAs) are involved in ribosome biogenesis and fine-tuning of translation. 5-Hydroxycytidine (ho5C), a modification of unknown biogenesis and function, is present at position 2501 of Escherichia coli 23S rRNA. We conducted a genome-wide screen in
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Leprosy is a chronic infectious disease that is caused by the obligate intracellular pathogen Mycobacterium leprae (M.leprae), which is the leading cause of all non-traumatic peripheral neuropathies worldwide. Although both myelinating and non-myelinating Schwann cells are infected by M.leprae in
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Information on fatty acid synthesis and metabolism in cancer cells. Learn how proliferatively active cells require fatty acids for functions such as membrane generation, protein modification, and bioenergetic requirements. These fatty acids are derived either from dietary sources or are synthesized by the cell.
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