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生物源
goat
共軛
alkaline phosphatase conjugate
抗體表格
affinity isolated antibody
抗體產品種類
secondary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous glycerol solution
物種活性
human
技術
direct ELISA: 1:30,000
dot blot: 1:30,000
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50
western blot: 1:30,000
運輸包裝
wet ice
儲存溫度
2-8°C
目標翻譯後修改
unmodified
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一般說明
免疫球蛋白M（IgM）抗体出现在感染过程的早期。 IgM抗体负责错配输血中的红细胞凝集。IgM的水平可能随疾病或感染的状况而变化。
碱性磷酸酶是可以催化对硝基苯磷酸(PNPP)等显色底物转化的酶；分别将发光底物（如CDP-Star）®和荧光底物（如4-甲基伞形酮磷酸酯/4-MUP）转化成为可检测色素、发光剂或荧光剂。
碱性磷酸酶是可以催化对硝基苯磷酸(PNPP)等显色底物转化的酶；分别将发光底物（如CDP-Star）®和荧光底物（如4-甲基伞形酮磷酸酯/4-MUP）转化成为可检测色素、发光剂或荧光剂。
在应答外部抗原第一次刺激时，人IgM是血液中最早出现的免疫球蛋白亚型。这类免疫球蛋白参与中枢神经系统(CNS)髓鞘修复。分泌型IgM水平升高与鼻结膜炎有关。当针对人IgA、IgG、IgM、本周蛋白κ和λ骨髓瘤蛋白进行测试时，抗人IgM（μ-链特异性）-碱性磷酸酶抗体对人IgM具有特异性。
免疫原
人IgM
應用
IgM是一种糖蛋白，重链上具有5个n连接的糖基化位点。可通过ELISA分析确定结合凝集素的IgM的糖基化形式，其中碱性磷酸酶标记的山羊抗人IgM可作为二抗（1:2000稀释），以对硝基苯基为底物(Sigma)。
山羊抗人IgM（μ-链特异性异性）-碱性磷酸酶抗体可用于斑点杂交和蛋白质免疫印迹分析（稀释度1:30,000）。
山羊抗人IgM（μ-链特异性）-碱性磷酸酶多克隆抗体可用于通过显色、化学发光和荧光免疫化学及免疫组织化学技术检测和定量人血清和生物体液中的IgM水平。
抗人IgM（μ-链特异性）-碱性磷酸酶抗体适用于ELISA。
外觀
溶剂为0.05 M Tris缓冲液，pH 8.0，含1 mM MgCl2、10 mM甘氨酸、1%牛血清白蛋白、50%甘油和15 mM叠氮化钠
法律資訊
CDP-Star is a registered trademark of Tropix, Inc.
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的人类或动物食用或应用。
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
其他客户在看
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In a seroprevalence study including 495 sera from persons of all age-groups, the presence of anti-Cryptosporidium parvum antibodies was evaluated in an enzyme immunoassay. Despite the fact that C. parvum is only found in approximately 2% of patients with diarrhea
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Journal of thrombosis and haemostasis : JTH, 16(1), 31-35 (2017-10-19)
Essentials Natural antibodies to oxidation-specific epitopes have antithrombotic properties. We evaluated the relation between natural IgM and IgG antibodies and the venous thrombosis risk. Risk of recurrent thrombosis was higher in patients with low natural IgM antibody levels. The protective
Meng-Yun Chou et al.
The Journal of clinical investigation, 119(5), 1335-1349 (2009-04-14)
Atherosclerosis is a chronic inflammatory disease characterized by the accumulation of oxidized lipoproteins and apoptotic cells. Adaptive immune responses to various oxidation-specific epitopes play an important role in atherogenesis. However, accumulating evidence suggests that these epitopes are also recognized by
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Clinical and experimental immunology, 136(2), 365-372 (2004-04-17)
Hodgkin's lymphoma patients treated with an anti-CD25 Ricin toxin A-chain (RTA)-based Immunotoxin (RFT5.dgA) develop an immune response against the toxic moiety of the immunoconjugate. The anti-RTA antibody response of 15 patients showing different clinical features and receiving different total amounts
商品
Antibody-based serology tests are useful in identifying subjects with an adaptive immune response to the SARS-CoV-2 virus. Anti-human immunoglobulin antibodies allow for quick and simple, yet reliable assays with easy readouts and can also be adapted for high-throughput screening.
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