75351

Oligomycin A

≥99% (HPLC)

• 别名: MCH 32
• 经验公式（希尔记法）: C₄₅H₇₄O₁₁
• CAS号: 579-13-5
• 分子量: 791.06
• Beilstein: 5702132
• EC號碼: 209-437-3
• MDL號碼: MFCD00065705
• 分類程式碼代碼: 51102829
• PubChem物質ID: 57652563
• NACRES: NA.76

属性

• 化驗: ≥99% (HPLC)
• 形狀: powder
• 顏色: white to off-white
• 溶解度: DMSO: soluble
• 抗生素活性譜: fungi
• 作用方式: enzyme | inhibits
• 儲存溫度: −20°C
• SMILES 字串: CCC1CCC2OC3(CC[C@@H](C)C(C[C@H](C)O)O3)[C@H](C)C(OC(=O)\C=C\[C@@H](C)[C@H](O)[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@H](C)C(=O)[C@@](C)(O)[C@H](O)[C@@H](C)C\C=C\C=C\1)[C@H]2C
• InChI: 1S/C45H74O11/c1-12-34-17-15-13-14-16-27(4)42(51)44(11,53)43(52)32(9)40(50)31(8)39(49)30(7)38(48)26(3)18-21-37(47)54-41-29(6)35(20-19-34)55-45(33(41)10)23-22-25(2)36(56-45)24-28(5)46/h13-15,17-18,21,25-36,38,40-42,46,48,50-51,53H,12,16,19-20,22-24H2,1-11H3/b14-13+,17-15+,21-18+/t25-,26-,27+,28+,29+,30-,31+,32+,33-,34?,35?,36?,38+,40-,41?,42-,44+,45?/m1/s1
• InChI 密鑰: MNULEGDCPYONBU-VVXVDZGXSA-N

说明

一般說明

Chemical structure: macrolide

應用

Oligomycin was used to inhibit sucrose synthesis and ¹⁴C translocation in sunflower leaves, to study antibiotic resistance, and to study carotid chemoreceptor responses to O₂ and CO₂ in the cat. Inhibits the growth of Rhodotorula glutinis, Aspergillus niger and other molds.

生化／生理作用

Oligomycin blocks oxidative phosphorylation and the electron transport chain by inhibiting membrane bound mitochondrial ATP synthase (ATPase) and proton channel (pump, FO subunit) blocker.

包裝

Bottomless glass bottle. Contents are inside inserted fused cone.

其他說明

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place. Keep in a dry place.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves