D2975000

阿霉素 盐酸盐

European Pharmacopoeia (EP) Reference Standard

• 别名: DOX, 多柔比星^® 盐酸盐, 羟基柔红霉素 盐酸盐
• 经验公式（希尔记法）: C₂₇H₂₉NO₁₁ · HCl
• CAS号: 25316-40-9
• 分子量: 579.98
• Beilstein: 4229251
• EC號碼: 246-818-3
• MDL號碼: MFCD00077757
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329798767
• NACRES: NA.24

属性

• 等級: pharmaceutical primary standard
• API 家族: doxorubicin
• 製造商／商標名: EDQM
• mp: 216 °C (dec.) (lit.)
• 應用: pharmaceutical (small molecule)
• 格式: neat
• SMILES 字串: Cl[H].COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO
• InChI: 1S/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3;1H/t10-,13-,15-,17-,22+,27-;/m0./s1
• InChI 密鑰: MWWSFMDVAYGXBV-RUELKSSGSA-N
• 基因資訊: human ... TOP2A(7153)

说明

一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, has been developed and issued under the Authority of the Issuing Pharmacopoeia.

For further information and support please go to the website of the issuing Pharmacopoeia.

Produced by certain strains of Streptomyces coeruleorubidus or Streptomyces peucetius or obtained by any other means.

應用

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia. Their suitability for any other use is not guaranteed and is the sole responsibility of the user. This standard is not intended for human or animal use.
Established for the preparation of the below-given solutions as per European Pharmacopoeia:

• Reference solutions (b) and (c) in the testing of related substances in daunorubicin hydrochloride using liquid chromatography (General text 2.2.29), according to the monograph 0662
• Reference solutions (a) and (c) to test related substances in doxorubicin hydrochloride using liquid chromatography (General text 2.2.29), according to the monograph 0714
• Reference solutions (b) and (c) in the testing of related substances in epirubicin hydrochloride using liquid chromatography (General text 2.2.29), according to the monograph 1590

包裝

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他說明

Sales restrictions may apply.

安全信息

• 象形圖: GHS08,GHS07
• 訊號詞: Danger
• 危險聲明: H302,H340,H350,H360FD
• 防範說明: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• 危險分類: Acute Tox. 4 Oral - Carc. 1B - Muta. 1B - Repr. 1B
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable