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等級
analytical standard
品質等級
化驗
≥98.0% (HPLC)
儲存期限
limited shelf life, expiry date on the label
技術
HPLC: suitable
gas chromatography (GC): suitable
雜質
≤1.0% water
應用
forensics and toxicology
pharmaceutical (small molecule)
格式
neat
SMILES 字串
O=C(C1=CC=C(OC(C)(C)C(O)=O)C=C1)C2=CC=C(Cl)C=C2
InChI
1S/C17H15ClO4/c1-17(2,16(20)21)22-14-9-5-12(6-10-14)15(19)11-3-7-13(18)8-4-11/h3-10H,1-2H3,(H,20,21)
InChI 密鑰
MQOBSOSZFYZQOK-UHFFFAOYSA-N
基因資訊
human ... PPARA(5465)
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應用
Fenofibric acid may be used as a reference standard in the determination of fenofibric acid in samples of human plasma using high performance liquid chromatography (HPLC) and liquid chromatography coupled with tandem mass spectrometry (LC-MS-MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
訊號詞
Warning
危險聲明
危險分類
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
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Simultaneous determination of rosuvastatin and fenofibric acid in human plasma by LC?MS/MS with electrospray ionization: assay development, validation and application to a clinical study.
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Journal of Pharmaceutical and Biomedical Analysis, 39(3-4), 661-669 (2005)
Determination of bezafibrate, ciprofibrate and fenofibric acid in human plasma by high-performance liquid chromatography.
Masnatta D L, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 687(2), 437-442 (1996)
Roger K Verbeeck et al.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 18(1), 61-67 (2015-04-17)
The therapeutic equivalence of multiple registered fenofibrate formulations, several of which are suprabioavailable and therefore marketed at lower dosage strengths than their reference products, is based on the results of bioequivalence studies. Most of these formulations show a higher bioavailability
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Biochemical and biophysical research communications, 458(1), 1-7 (2015-01-17)
Fenofibrate (FF) is widely used to lower blood lipids in clinical practice, but whether its protective effect on endothelium-dependent vasodilatation (EDV) in thoracic aorta is related with endoplasmic reticulum (ER) stress remains unknown. In this study, female Sprauge Dawley rats
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Biochimica et biophysica acta, 1851(2), 231-237 (2014-12-17)
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