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化驗
≥98% (HPLC)
形狀
powder
光學活性
[α]/D +19 to +24°, c = 1 in acetonitrile: water (1:1)
儲存條件
desiccated
顏色
white to beige
溶解度
DMSO: 2 mg/mL, clear
儲存溫度
2-8°C
SMILES 字串
[Ca+2].Fc5ccc(cc5)c6c7c(nc(c6\C=C\[C@@H](O)C[C@@H](O)CC(=O)[O-])C8CC8)cccc7.Fc1ccc(cc1)c2c3c(nc(c2\C=C\[C@@H](O)C[C@@H](O)CC(=O)[O-])C4CC4)cccc3
InChI
1S/2C25H24FNO4.Ca/c2*26-17-9-7-15(8-10-17)24-20-3-1-2-4-22(20)27-25(16-5-6-16)21(24)12-11-18(28)13-19(29)14-23(30)31;/h2*1-4,7-12,16,18-19,28-29H,5-6,13-14H2,(H,30,31);/q;;+2/p-2/b2*12-11+;/t2*18-,19-;/m11./s1
InChI 密鑰
RHGYHLPFVJEAOC-FFNUKLMVSA-L
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生化／生理作用
HMG CoA reductase inhibitor
Pitavastatin calcium is a water-soluble inhibitor of hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Pitavastatin calcium is antilipidemic and is used to reduce plasma cholesterol levels and prevent cardiovascular disease.
訊號詞
Warning
危險聲明
危險分類
Repr. 2
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
其他客户在看
Sheridan M Hoy
American journal of cardiovascular drugs : drugs, devices, and other interventions, 17(2), 157-168 (2017-01-29)
Oral pitavastatin (Livalo®; Livazo®) is a competitive HMG-CoA reductase inhibitor that is available in the EU for the reduction of elevated total cholesterol and low-density lipoprotein cholesterol (LDL-C) levels in adults with primary hypercholesterolemia and combined (mixed) dyslipidemia. In short-term
Jah Yeon Choi et al.
The American journal of cardiology, 122(6), 922-928 (2018-09-16)
Although statin use in patients with acute myocardial infarction (AMI) is mandatory, it has been suggested to be associated with new-onset diabetes mellitus (NODM). In real world practice, moderate-intensity statin therapy is more commonly used than high-intensity statin therapy. In
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