所有图片(1)
About This Item
经验公式（希尔记法）:
C10H11ClN2O2
CAS号:
分子量:
226.66
Beilstein:
4440901
MDL號碼:
分類程式碼代碼:
12352108
PubChem物質ID:
NACRES:
NA.32
推荐产品
品質等級
化驗
≥70.0% (HPCE)
形狀
powder
mp
135-136 °C (lit.)
溶解度
DMF: soluble
DMSO: soluble
acetonitrile: soluble
methanol: soluble
螢光
λex 380 nm; λem 461 nm in methanol
λex 390 nm; λem 478 nm in 0.1 M phosphate pH 7.5 (after derivatization with glutathione)
適合性
suitable for fluorescence
SMILES 字串
CC1=C(C)C(=O)N2N1C(CCl)=C(C)C2=O
InChI
1S/C10H11ClN2O2/c1-5-7(3)12-8(4-11)6(2)10(15)13(12)9(5)14/h4H2,1-3H3
InChI 密鑰
SUIPVTCEECPFIB-UHFFFAOYSA-N
一般說明
单氯二胺是一种可渗透入细胞的谷胱甘肽（GSH）荧光探针。当与待测试细胞培养物共同孵育时，它可以轻易进入细胞并形成荧光复合物。单氯二胺-GSH反应由谷胱甘肽-S-转移酶催化，可使用荧光法检测。
单氯二胺又名mBCl，是一种反应前不发荧光，反应后形成荧光复合物的化合物。 荧光可在394/490nm处被检测到。
单氯二胺又名mBCl，是一种反应前不发荧光，反应后形成荧光复合物的化合物。 荧光可在394/490nm处被检测到。
應用
单氯二胺在荧光谷胱甘肽测定中用作荧光剂。 它被用于检测主要细胞内小分子量的硫醇，这些硫在防御机制中起关键作用。
包裝
无底玻璃瓶。内含物装在插入的融合锥内。
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
其他客户在看
Jordi Sebastià et al.
Cytometry. Part A : the journal of the International Society for Analytical Cytology, 51(1), 16-25 (2002-12-25)
Reduced glutathione (GSH) protects cells against oxidative injury and maintains a range of vital functions. To study GSH content in human neuronal cell cultures, thiol-sensitive fluorescent techniques requiring a small number of cells may be of great value, but their
Natascha Rauch et al.
Insect biochemistry and molecular biology, 34(4), 321-329 (2004-03-26)
Glutathione S-transferases (GST) catalyzing the conjugation of reduced glutathione to a vast range of xenobiotics including insecticides were characterized in the whitefly Bemisia tabaci. GST activities were determined in susceptible and resistant strains of B. tabaci towards artificial substrates, i.e.
S Nair et al.
Cytometry, 12(4), 336-342 (1991-01-01)
We have used an enzymatic (spectro-photometric) and a flow cytometric (GSH-MBCL) method to compare the glutathione (GSH) content of doxorubicin sensitive (P388) and resistant (P388/R-84) murine leukemic and human lung cancer cells. The flow cytometric analysis revealed that GSH-MBCL conjugate
Formation and rapid export of the monochlorobimane-glutathione conjugate in cultured rat astrocytes.
Jens Waak et al.
Neurochemical research, 31(12), 1409-1416 (2006-11-08)
Monochlorobimane (MCB) is often used to visualize glutathione (GSH) levels in cultured cells, since it is quickly converted to a fluorescent GSH conjugate (GS-MCB). To test for consequences of MCB application on the GSH metabolism of astrocytes, we have studied
Madushi Raththagala et al.
Analytical chemistry, 78(24), 8556-8560 (2006-12-15)
A method for the quantitative determination of the antioxidant form of glutathione (GSH) in red blood cells (RBCs) is described that does not require separation of the analyte of interest from the complex cellular matrix. The measurement portion of the
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门