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生物源
synthetic (organic)
化驗
≥97% (TLC)
形狀
powder
mp
224-226 °C
溶解度
water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
運輸包裝
wet ice
儲存溫度
−20°C
SMILES 字串
CCCCS(=N)(=O)CC[C@H](N)C(O)=O
InChI
1S/C8H18N2O3S/c1-2-3-5-14(10,13)6-4-7(9)8(11)12/h7,10H,2-6,9H2,1H3,(H,11,12)/t7-,14?/m0/s1
InChI 密鑰
KJQFBVYMGADDTQ-CVSPRKDYSA-N
基因資訊
human ... GCLC(2729) , GCLM(2730)
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應用
L丁硫氨酸-亚砜亚胺已用作:
- 选择性激活剂,以诱导大鼠凋亡细胞的铁死亡
- γ谷氨酰半胱氨酸合成酶抑制剂,以研究其对小黑麦和大麦小孢子胚胎发生(ME)诱导活力和效果的影响
- 谷胱甘肽合成阻断剂,以研究其在小鼠肺泡巨噬细胞中金诺芬(AFN)介导的白介素-1β表达的影响
用于诱导实验性谷胱甘肽缺乏,以研究谷胱甘肽在细胞过程中的作用。
生化/生理作用
通过抑制谷胱甘肽生物合成中的关键酶γ-谷氨酰半胱氨酸合成酶,进而阻断对化疗的细胞抵抗性。用于诱导实验性谷胱甘肽缺乏,以研究谷胱甘肽在细胞过程中的作用。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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