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Key Documents

8.51005

Sigma-Aldrich

DSC

≥99.0% (HPLC), for peptide synthesis, Novabiochem®

别名:

DSC, N,N′-Disuccinimidyl carbonate, Di-(N-Succinimidyl)carbonate

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About This Item

经验公式(希尔记法):
C9H8N2O7
CAS号:
分子量:
256.17
MDL號碼:
分類程式碼代碼:
12352108
酶委員會索引編號:
277-730-3
NACRES:
NA.22

product name

DSC, N,N′-Disuccinimidyl carbonate Novabiochem®

品質等級

產品線

Novabiochem®

化驗

≥99.0% (HPLC)

形狀

powder

反應適用性

reaction type: Coupling Reactions

製造商/商標名

Novabiochem®

mp

188-191 °C

應用

peptide synthesis

儲存溫度

2-8°C

InChI

1S/C9H8N2O7/c12-5-1-2-6(13)10(5)17-9(16)18-11-7(14)3-4-8(11)15/h1-4H2

InChI 密鑰

PFYXSUNOLOJMDX-UHFFFAOYSA-N

一般說明

A convenient reagent for the synthesis of N-succinimidyl esters of N-protected amino acids [1,2,3,4].

Associated Protocols and Technical Articles
Guide to Selection of Coupling Reagents

Literature references

[1] H. Ogura, et al. (1979) Tetrahedron Lett., 20, 4745.
[2] H. Ogura, et al. (1981) Tetrahedron Lett., 22, 4817.
[3] K. Takeda, et al. (1982) Synth. Commun., 12, 213.
[4] K. Takeda, et al. (1983) TetrahedronLett., 24, 4569.

應用

  • Utilization in solid-phase peptide synthesis: Discusses the role of N,N′-disuccinimidyl carbonate in solid-phase peptide synthesis, providing insights into its effectiveness in enhancing coupling reactions (Meschaninova et al., 2019).
  • Surface functionalization of polymeric materials: This article explores the application of N,N′-disuccinimidyl carbonate in the surface functionalization of polymers to improve their biocompatibility and interaction with biological molecules (Yakufu et al., 2020).
  • Development of affinity chromatography technologies: Details the use of N,N′-disuccinimidyl carbonate in the development of novel affinity chromatography approaches for protein purification (Hinamoto et al., 2023).
  • Enhancement of polymer properties: Investigates how N,N′-disuccinimidyl carbonate can be used to modify polymer surfaces to enhance their properties, such as increased hydrophilicity and reactivity (Swar et al., 2020).

聯結

Replaces: 01-62-0006

分析報告

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Assay (HPLC, area%): ≥ 99.0 % (a/a)
Water (K. F.): ≤ 0.50 %
Identity (IR): passes test

法律資訊

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

象形圖

Exclamation markHealth hazard

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral - Eye Irrit. 2 - STOT RE 2 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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