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Merck
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文件

107700

Sigma-Aldrich

4-(二甲氨基)吡啶

ReagentPlus®, ≥99%

别名:

N,N-二甲基-4-吡啶胺, DMAP

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About This Item

经验公式（希尔记法）:
C7H10N2
CAS号:
1122-58-3
分子量:
122.17
Beilstein:
110354
EC號碼:
214-353-5
MDL號碼:
MFCD00006418
分類程式碼代碼:
12352302
PubChem物質ID:
24846774
NACRES:
NA.22

品質等級

200

產品線

ReagentPlus®

化驗

≥99%

形狀

chips
crystalline powder
flakes

mp

108-110 °C (lit.)

溶解度

H2O: 50 mg/mL

儲存溫度

room temp

SMILES 字串

CN(C)c1ccncc1

InChI

1S/C7H10N2/c1-9(2)7-3-5-8-6-4-7/h3-6H,1-2H3

InChI 密鑰

VHYFNPMBLIVWCW-UHFFFAOYSA-N

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相关类别

一般說明

4-二甲氨基吡啶（DMAP）是一种多功能亲核催化剂，用于酰化和酯化反应。它也可用于各种有机转化反应，如Baylis-Hillman反应、Dakin-West反应、胺的保护、C-酰化、硅烷化、天然产物化学中的应用。

應用

4-二甲氨基吡啶可用作以下反应的催化剂：
  • 通过与丙二腈、醛和β-硝基烯反应合成3,5 取代的2,6-二氰基苯胺。
  • 在无辅助碱和溶剂的条件下与酸酐进行醇的酰化反应合成相应的酯。
  • 通过活化烯和醛或酮的偶联进行Baylis-Hillman 反应生成碳碳键。
酰化反应的高效催化剂

法律資訊

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

訊號詞

Danger

危險分類

Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 1

標靶器官

Nervous system

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類（WGK）

WGK 3

閃點（°F）

255.2 °F

閃點（°C）

124 °C

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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