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Merck

205249

Sigma-Aldrich

二碳酸二叔丁酯

99%, for peptide synthesis, ReagentPlus®

别名:

二叔丁基二碳酸酯, 焦碳酸二叔丁酯

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About This Item

线性分子式:
[(CH3)3COCO]2O
CAS号:
分子量:
218.25
Beilstein:
1911173
EC號碼:
MDL號碼:
分類程式碼代碼:
12352302
PubChem物質ID:
NACRES:
NA.22

product name

二碳酸二叔丁酯, ReagentPlus®, 99%

品質等級

產品線

ReagentPlus®

化驗

99%

形狀

solid or liquid

折射率

n20/D 1.409 (lit.)

bp

56-57 °C/0.5 mmHg (lit.)

mp

23 °C (lit.)

密度

0.95 g/mL at 25 °C (lit.)

應用

peptide synthesis

儲存溫度

2-8°C

SMILES 字串

CC(C)(C)OC(=O)OC(=O)OC(C)(C)C

InChI

1S/C10H18O5/c1-9(2,3)14-7(11)13-8(12)15-10(4,5)6/h1-6H3

InChI 密鑰

DYHSDKLCOJIUFX-UHFFFAOYSA-N

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應用

Boc保护胺制备溶剂。
Tris-Boc保护的肼可在显色试剂中制备Fmoc酯以监测固相醛。

使用Synple自动合成平台(SYNPLE-SC002)、Boc保护试剂盒((SYNPLE-B001)、(SYNPLE-B002)和Boc脱保护试剂盒(SYNPLE-B011),可自动进行Boc保护和脱保护
用于引入Boc保护基的试剂。
通过 Lewis 酸催化作用可以保护叔丁氧羰基衍生物等醇类。
通过叔丁氧羰基氨基丙炔与甲醛、二异丙胺以及溴化铜的反应来制备氨甲基丙二烯,是许多牛血浆胺氧化酶灭活剂的组分。

警告

水解为叔丁醇和 CO2;暴露在潮湿环境中会导致瓶内压力增大。

法律資訊

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

訊號詞

Danger

危險分類

Acute Tox. 1 Inhalation - Eye Dam. 1 - Flam. Liq. 3 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

98.6 °F - closed cup

閃點(°C)

37 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Simon K Shannon et al.
The Journal of organic chemistry, 69(14), 4586-4594 (2004-07-03)
A direct method for quantifying solid-phase aldehydes has been developed, using a new reagent, 4-(9-fluorenylmethyloxycarbonyl)phenylhydrazine (FmPH). The FmPH reagent was synthesized in three steps (24% overall yield) from commercially available p-hydrazinobenzoic acid. Resin-bound aldehydes reacted quantitatively with FmPH, in the
Chunhua Qiao et al.
Journal of the American Chemical Society, 126(25), 8038-8045 (2004-06-24)
Propargylic and activated allylic amines are known to inactivate the quinone-dependent plasma amine oxidases, possibly through active-site modification by the alpha,beta-unsaturated aldehyde turnover products. Although homopropargylamine (1-amino-3-butyne, 1) is a nonobvious candidate as a mechanism-based inhibitor, 1 was found to
Synthetic Communications, 23, 1443-1443 (1993)
Synlett, 2104-2104 (2006)
Hans Peter Reisenauer et al.
Angewandte Chemie (International ed. in English), 53(44), 11766-11771 (2014-09-10)
Carbonic acid (H2CO3), an essential molecule of life (e.g., as bicarbonate buffer), has been well characterized in solution and in the solid state, but for a long time, it has eluded its spectral characterization in the gas phase owing to

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