推荐产品
化驗
≥95% (HPLC)
品質等級
形狀
liquid
製造商/商標名
Calbiochem®
儲存條件
OK to freeze
protect from light
螢光
λex 335 nm (high)
λex 362 nm (low)
λem 505 nm (high)
λem 512 nm (low)
運輸包裝
ambient
儲存溫度
−20°C
InChI
1S/C44H47N3O24/c1-25-7-8-32(46(16-38(53)65-20-60-26(2)48)17-39(54)66-21-61-27(3)49)35(13-25)58-11-12-59-42-31-14-36(43-45-15-37(71-43)44(57)69-24-64-30(6)52)70-34(31)10-9-33(42)47(18-40(55)67-22-62-28(4)50)19-41(56)68-23-63-29(5)51/h7-10,13-15H,11-12,16-24H2,1-6H3
InChI 密鑰
UTBYGIDPBQOHNT-UHFFFAOYSA-N
一般說明
Cell-permeable ester form of FURA 2 (Cat. No. 344900). The active dye is rapidly released in the cell by cytoplasmic esterases. Fluorescent calcium chelator (Kd = 224 nM) that offers 30X greater fluorescence intensity that QUIN 2 (Cat. No. 551826). This probe has been used as a probe in many cellular systems, including cardiac myocytes, vascular smooth muscle cells, and medullary collecting tubules. Spectral properties in the presence of low calcium concentrations (excitation max.: 362 nm, emission max.: 512 nm) differ from those during high calcium conditions (excitation max.: 335 nm, emission max.: 505 nm).
生化/生理作用
Cell permeable: no
Product does not compete with ATP.
Reversible: no
包裝
Packaged under inert gas
警告
Toxicity: Irritant (B)
外觀
A 1 mM solution of FURA 2/AM (Cat. No. 344905) in anhydrous DMSO.
重構
Following initial thaw, aliquot and freeze (-20°C). Store frozen under an inert atmosphere.
其他說明
Davis, M.J., et al. 1992. Am. J. Physiol. 263, H1292.
Rao, G.H., et al. 1992. Biochem. Med. Metab. Biol.47, 226.
Schwartz, Y., et al. 1992. Endocrinology131, 772.
Ward, C.A., and Moffat, M.P. 1992. J. Mol. Cell. Cardiol.24, 937.
Janconi, M.E., et al. 1990. J. Cell Biol.110, 1555.
Tsien, R.Y. 1980. Biochemistry19, 2396.
Rao, G.H., et al. 1992. Biochem. Med. Metab. Biol.47, 226.
Schwartz, Y., et al. 1992. Endocrinology131, 772.
Ward, C.A., and Moffat, M.P. 1992. J. Mol. Cell. Cardiol.24, 937.
Janconi, M.E., et al. 1990. J. Cell Biol.110, 1555.
Tsien, R.Y. 1980. Biochemistry19, 2396.
法律資訊
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 1
閃點(°F)
188.6 °F - closed cup - (Dimethylsulfoxide)
閃點(°C)
87 °C - closed cup - (Dimethylsulfoxide)
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