344906

FURA 2/AM in Solution

• 别名: FURA 2/AM in Solution
• 经验公式（希尔记法）: C₄₄H₄₇N₃O₂₄
• CAS号: 108964-32-5
• 分子量: 1001.85
• MDL號碼: MFCD00036976
• 分類程式碼代碼: 12171500
• NACRES: NA.47

属性

• 化驗: ≥95% (HPLC)
• 品質等級: 100
• 形狀: liquid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; protect from light
• 螢光: λ_ex 335 nm (high); λ_ex 362 nm (low); λ_em 505 nm (high); λ_em 512 nm (low)
• 運輸包裝: ambient
• 儲存溫度: −20°C
• SMILES 字串: N(CC(=O)OCOC(=O)C)(CC(=O)OCOC(=O)C)c1c(cc(cc1)C)OCCOc2c3c([o]c(c3)c4ncc([o]4)C(=O)OCOC(=O)C)ccc2N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C
• InChI: 1S/C44H47N3O24/c1-25-7-8-32(46(16-38(53)65-20-60-26(2)48)17-39(54)66-21-61-27(3)49)35(13-25)58-11-12-59-42-31-14-36(43-45-15-37(71-43)44(57)69-24-64-30(6)52)70-34(31)10-9-33(42)47(18-40(55)67-22-62-28(4)50)19-41(56)68-23-63-29(5)51/h7-10,13-15H,11-12,16-24H2,1-6H3
• InChI 密鑰: UTBYGIDPBQOHNT-UHFFFAOYSA-N

说明

一般說明

Cell-permeable ester form of FURA 2 (Cat. No. 344900). The active dye is rapidly released in the cell by cytoplasmic esterases. Fluorescent calcium chelator (K_d = 224 nM) that offers 30X greater fluorescence intensity that QUIN 2 (Cat. No. 551826). This probe has been used as a probe in many cellular systems, including cardiac myocytes, vascular smooth muscle cells, and medullary collecting tubules. Spectral properties in the presence of low calcium concentrations (excitation max.: 362 nm, emission max.: 512 nm) differ from those during high calcium conditions (excitation max.: 335 nm, emission max.: 505 nm).

生化／生理作用

Cell permeable: no

Product does not compete with ATP.

Reversible: no

包裝

Packaged under inert gas

警告

Toxicity: Irritant (B)

外觀

A 1 mM solution of FURA 2/AM (Cat. No. 344905) in anhydrous DMSO.

重構

Following initial thaw, aliquot and freeze (-20°C). Store frozen under an inert atmosphere.

其他說明

Davis, M.J., et al. 1992. Am. J. Physiol. 263, H1292.
Rao, G.H., et al. 1992. Biochem. Med. Metab. Biol.47, 226.
Schwartz, Y., et al. 1992. Endocrinology131, 772.
Ward, C.A., and Moffat, M.P. 1992. J. Mol. Cell. Cardiol.24, 937.
Janconi, M.E., et al. 1990. J. Cell Biol.110, 1555.
Tsien, R.Y. 1980. Biochemistry19, 2396.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: 188.6 °F - closed cup - (Dimethylsulfoxide)
• 閃點（°C）: 87 °C - closed cup - (Dimethylsulfoxide)