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Merck
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主要文件

344906

Sigma-Aldrich

FURA 2/AM in Solution

别名:

FURA 2/AM in Solution

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About This Item

经验公式(希尔记法):
C44H47N3O24
分子量:
1001.85
MDL號碼:
分類程式碼代碼:
12171500
NACRES:
NA.47

化驗

≥95% (HPLC)

品質等級

形狀

liquid

製造商/商標名

Calbiochem®

儲存條件

OK to freeze
protect from light

螢光

λex 335 nm (high)
λex 362 nm (low)
λem 505 nm (high)
λem 512 nm (low)

運輸包裝

ambient

儲存溫度

−20°C

InChI

1S/C44H47N3O24/c1-25-7-8-32(46(16-38(53)65-20-60-26(2)48)17-39(54)66-21-61-27(3)49)35(13-25)58-11-12-59-42-31-14-36(43-45-15-37(71-43)44(57)69-24-64-30(6)52)70-34(31)10-9-33(42)47(18-40(55)67-22-62-28(4)50)19-41(56)68-23-63-29(5)51/h7-10,13-15H,11-12,16-24H2,1-6H3

InChI 密鑰

UTBYGIDPBQOHNT-UHFFFAOYSA-N

一般說明

Cell-permeable ester form of FURA 2 (Cat. No. 344900). The active dye is rapidly released in the cell by cytoplasmic esterases. Fluorescent calcium chelator (Kd = 224 nM) that offers 30X greater fluorescence intensity that QUIN 2 (Cat. No. 551826). This probe has been used as a probe in many cellular systems, including cardiac myocytes, vascular smooth muscle cells, and medullary collecting tubules. Spectral properties in the presence of low calcium concentrations (excitation max.: 362 nm, emission max.: 512 nm) differ from those during high calcium conditions (excitation max.: 335 nm, emission max.: 505 nm).

生化/生理作用

Cell permeable: no
Product does not compete with ATP.
Reversible: no

包裝

Packaged under inert gas

警告

Toxicity: Irritant (B)

外觀

A 1 mM solution of FURA 2/AM (Cat. No. 344905) in anhydrous DMSO.

重構

Following initial thaw, aliquot and freeze (-20°C). Store frozen under an inert atmosphere.

其他說明

Davis, M.J., et al. 1992. Am. J. Physiol. 263, H1292.
Rao, G.H., et al. 1992. Biochem. Med. Metab. Biol.47, 226.
Schwartz, Y., et al. 1992. Endocrinology131, 772.
Ward, C.A., and Moffat, M.P. 1992. J. Mol. Cell. Cardiol.24, 937.
Janconi, M.E., et al. 1990. J. Cell Biol.110, 1555.
Tsien, R.Y. 1980. Biochemistry19, 2396.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

188.6 °F - closed cup - (Dimethylsulfoxide)

閃點(°C)

87 °C - closed cup - (Dimethylsulfoxide)


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