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About This Item
经验公式（希尔记法）:
C44H47N3O24
CAS号:
分子量:
1001.85
Beilstein:
8183748
MDL號碼:
分類程式碼代碼:
12171500
PubChem物質ID:
NACRES:
NA.47
推荐产品
product name
Fura 2-AM, ≥95% (HPLC)
品質等級
化驗
≥95% (HPLC)
形狀
powder
顏色
yellow to yellow-green
溶解度
acetone: 10 mg/mL
應用
diagnostic assay manufacturing
hematology
histology
儲存溫度
−20°C
SMILES 字串
CC(=O)OCOC(=O)CN(CC(=O)OCOC(C)=O)c1ccc(C)cc1OCCOc2cc3cc(oc3cc2N(CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O)-c4ncc(o4)C(=O)OCOC(C)=O
InChI
1S/C44H47N3O24/c1-25-7-8-32(46(16-39(53)65-20-60-26(2)48)17-40(54)66-21-61-27(3)49)35(11-25)58-9-10-59-36-12-31-13-37(43-45-15-38(71-43)44(57)69-24-64-30(6)52)70-34(31)14-33(36)47(18-41(55)67-22-62-28(4)50)19-42(56)68-23-63-29(5)51/h7-8,11-15H,9-10,16-24H2,1-6H3
InChI 密鑰
VPSRLGDRGCKUTK-UHFFFAOYSA-N
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一般說明
Fura 2- am（Fura 2）是一种钙特定比率荧光染料。它也被称为乙酰氧基甲酯。 为了响应钙离子，像Fura 2这样的比例度量染料改变了各自的激发或发射光谱。细胞内钙浓度由不同波长的荧光发射比或激发决定。Fura 2的发射峰在505nm，激发峰在340-380nm之间，是首选的钙指示剂。
應用
Fura 2-AM是一种常用的探针，用于测定完整活细胞中细胞质游离钙的动态变化。
特點和優勢
使用Fura 2的酯形式作为Fura 2-AM的主要好处有：可渗透细胞。容易载入细胞中。与单波长染料相比，使用Fura 2-AM的另一个优点是，比率信号与以下因素无关：染料浓度。照明强度、光程长度。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
J L Donato et al.
British journal of pharmacology, 119(7), 1447-1453 (1996-12-01)
1. Proteoglycans provide negatively charged sites on the surface of platelets, leukocytes and endothelial cells. Since chondroitin 4-sulphate is the main proteoglycan present on the platelet surface, the role of this molecule in mediating the activation of human platelets by
Assessment of intracellular Ca2+, cAMP and 1,2-diacylglycerol in cryopreserved buffalo (Bubalus bubalis) spermatozoa on supplementation of taurine and trehalose in the extender.
Singh VK
Reproduction in domestic animals = Zuchthygiene, 47, 584-584 (2012)
B T Kinsella et al.
The Journal of pharmacology and experimental therapeutics, 281(2), 957-964 (1997-05-01)
To establish whether the thromboxane A2 (TXA2) receptor (TP) functionally couples to the Gq family of heterotrimeric G proteins in vivo, we have coexpressed the cDNAs coding for the human platelet/placental TP alpha isoform (TP alpha) and the alpha subunits
Assessment of Fura-2 for measurements of cytosolic free calcium.
Roe MW
Cell Calcium, 11, 63-63 (1990)
Effects of Taurine or Trehalose supplementation on functional competence of cryopreserved Karan Fries semen.
Chhillar S
Animal Reproduction, 135, 1-1 (2012)
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