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Merck

P4170

Sigma-Aldrich

碘化丙啶

≥94.0% (HPLC)

别名:

3,8-二氨基-5-[3-(二乙基甲基氨基)丙基]-6-苯基菲啶二碘化物

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About This Item

经验公式(希尔记法):
C27H34I2N4
CAS号:
分子量:
668.39
Beilstein:
3843838
EC號碼:
MDL號碼:
分類程式碼代碼:
41106305
PubChem物質ID:
NACRES:
NA.77

品質等級

化驗

≥94.0% (HPLC)

形狀

powder

mp

220-225 °C (dec.) (lit.)

儲存溫度

2-8°C

SMILES 字串

[I-].[I-].CC[N+](C)(CC)CCC[n+]1c(-c2ccccc2)c3cc(N)ccc3c4ccc(N)cc14

InChI

1S/C27H33N4.2HI/c1-4-31(3,5-2)17-9-16-30-26-19-22(29)13-15-24(26)23-14-12-21(28)18-25(23)27(30)20-10-7-6-8-11-20;;/h6-8,10-15,18-19,29H,4-5,9,16-17,28H2,1-3H3;2*1H/q+1;;/p-1

InChI 密鑰

XJMOSONTPMZWPB-UHFFFAOYSA-M

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一般說明

碘化丙啶(PI)是一种荧光染料,可用于核酸染色。无法通过活细胞或完整细胞。可轻易进入死细胞、濒死细胞或膜受损细胞。碘化丙啶可轻松结合DNA。

應用

碘化丙啶用于:流式细胞术检测细胞周期,γH2AX和pH3分析,肝星状细胞(HSC)的凋亡试验,加入染色缓冲液/溶液中染色细胞以分析细胞周期

特點和優勢

该化合物是细胞凋亡研究的特色产品。点击此处以了解更多的细胞凋亡特色产品。可访问sigma.com/discover-bsm了解更多关于用于其他研究领域生物活性小分子。

象形圖

Health hazard

訊號詞

Warning

危險聲明

危險分類

Muta. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


分析证书(COA)

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Molecular immunology, 112, 312-321 (2019-06-24)
Precise glycosylation plays a crucial and distinctive role in thymic T cell development. The core fucosylation is dramatically up-regulated at the transition from CD4-CD8- (DN) to CD4+CD8+ (DP) in the thymic development. Ablation of core fucosylation in T cells did
Chi-Hyun Ahn et al.
International journal of molecular sciences, 20(14) (2019-07-19)
Norcantharidin (NCTD), a demethylated analog of cantharidin isolated from blister beetles, has been used as a promising anticancer agent; however, the underlying function of NCTD against human oral squamous cell carcinoma (OSCC) has not been fully understood. Here, this study
Yaser Atlasi et al.
Scientific reports, 9(1), 11928-11928 (2019-08-17)
Human embryonal carcinoma (EC) cells comprise the pluripotent stem cells of malignant non-seminomatous germ cell tumors (GCTs) and represent the malignant counterpart of embryonic stem cells (ESCs). WNT/β-catenin signaling has been implicated in regulating adult and embryonic stem cells although
Marcella Giovanni et al.
Journal of hazardous materials, 297, 146-152 (2015-05-10)
To cellular systems, nanoparticles are considered as foreign particles. Upon particles and cells contact, innate immune system responds by activating the inflammatory pathway. However, excessive inflammation had been linked to various diseases ranging from allergic responses to cancer. Common nanoparticles
Ramya Kumareswaran et al.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 116(3), 388-391 (2015-04-07)
Solid tumors contain regions of chronic and cyclic hypoxia. Chronic hypoxia can downregulate RAD51 and sensitize cells to PARP inhibition. Herein, we show that RAD51 expression, cell survival and toxicity to PARP inhibition is not affected under cyclic hypoxic conditions.

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The Comet Assay, also called single cell gel electrophoresis (SCGE), is a sensitive and rapid technique for quantifying and analyzing DNA damage in individual cells.

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