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Merck

137151

SAFC

2-巯基乙醇

EMPROVE® EVOLVE

制药生产

别名:

β-巯基乙醇, 2-羟乙基硫醇, BME, 硫代二甘醇

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About This Item

线性分子式:
HSCH2CH2OH
CAS号:
分子量:
78.13
Beilstein:
773648
MDL號碼:
分類程式碼代碼:
12161504

蒸汽密度

2.69 (vs air)

品質等級

蒸汽壓力

1 mmHg ( 20 °C)

形狀

liquid

expl. lim.

18 %

濃度

14.3 M (pure liquid)
99.0-101.0 % (w/w)

雜質

≤1.0% related substances (GC) 2,2-Dithiodiethanol

折射率

n20/D 1.500 (lit.)

bp

157 °C (lit.)

密度

1.114 g/mL at 25 °C (lit.)

適合性

corresponds for identity (IR)

應用

pharma/biopharma processes

儲存溫度

2-8°C

SMILES 字串

OCCS

InChI

1S/C2H6OS/c3-1-2-4/h3-4H,1-2H2

InChI 密鑰

DGVVWUTYPXICAM-UHFFFAOYSA-N

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相关类别

一般說明

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

As part of our EMPROVE® Program, our raw materials are offered with EMPROVE® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.

應用

BME is suitable for reducing protein disulfide bonds prior to polyacrylamide gel electrophoresis and is usually included in a sample buffer for SDS-PAGE at a concentration of 5%. Cleaving intermolecular (between subunits) disulfide bonds allows the subunits of a protein to separate independently on SDS-PAGE. Cleaving intramolecular (within subunit) disulfide bonds allows the subunits to become completely denatured so that each peptide migrates according to its chain length with no influence due to secondary structure.

分析報告

purity (GC) ≥99.0%

法律資訊

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

訊號詞

Danger

危險分類

Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 Oral

儲存類別代碼

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°C)

74 °C - closed cup


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