推荐产品
生物源
synthetic (organic)
品質等級
產品線
BioUltra
化驗
≥99% (NMR)
形狀
powder
雜質
≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter
mp
92-95 °C (lit.)
溶解度
H2O: 0.5 M, clear, colorless
負離子痕跡
chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%
正離子痕跡
Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%
儲存溫度
2-8°C
SMILES 字串
NC(=O)CI
InChI
1S/C2H4INO/c3-1-2(4)5/h1H2,(H2,4,5)
InChI 密鑰
PGLTVOMIXTUURA-UHFFFAOYSA-N
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應用
碘乙酰胺已用于：
- 蛋白质组学分析的蛋白质消化
- 烷基化蛋白质样品
- 牛奶过敏原、β-乳球蛋白（BLG）和α-乳清蛋白（ALA）的变性
生化／生理作用
碘乙酰胺（IAA）被用于抑制糖酵解，因为它能够不可逆地抑制糖酵解酶甘油醛-3-磷酸脱氢酶（GAPDH）。IAA用于研究半胱氨酸残基在酶催化和脑细胞转运过程中的作用。它可以与巯基乙醇和谷胱甘肽等低分子量硫醇化合物发生反应。IAN还可能阻断菠萝蛋白酶、组织蛋白酶C、梭状芽孢蛋白酶和羧肽酶P等酶。
碘乙酰胺在肽测序中胱氨酸残基的烷基化试剂。它是活性位点上含有胱氨酸的酶的的一种不可逆抑制剂。它与组氨酸残基的反应速度要慢得多，但这种活性是核糖核酸酶抑制的原因。
訊號詞
Danger
危險分類
Acute Tox. 3 Oral - Aquatic Chronic 4 - Resp. Sens. 1 - Skin Sens. 1
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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