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Merck

860586P

Avanti

18:0 SM (d18:1/18:0)

Avanti Research - A Croda Brand 860586P, powder

别名:

N-硬脂酰-D-赤-鞘氨醇磷酸胆碱

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About This Item

经验公式(希尔记法):
C41H83N2O6P
CAS号:
分子量:
731.08
MDL號碼:
分類程式碼代碼:
12352211
NACRES:
NA.25

形狀

powder

包裝

pkg of 1 × 10 mg (860586P-10mg)
pkg of 1 × 5 mg (860586P-5mg)

製造商/商標名

Avanti Research - A Croda Brand 860586P

脂質類型

sphingolipids

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCCC)=O)COP([O-])(OCC[N+](C)(C)C)=O

InChI

1S/C41H83N2O6P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-41(45)42-39(38-49-50(46,47)48-37-36-43(3,4)5)40(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h32,34,39-40,44H,6-31,33,35-38H2,1-5H3,(H-,42,45,46,47)/b34-32+/t39-,40+/m0/s1

InChI 密鑰

LKQLRGMMMAHREN-YJFXYUILSA-N

應用

N-硬脂酰-D-赤型-鞘氨醇磷酸胆碱(18:0 SM (d18:1/18:0))已用于:
  • 作为脂质体组分测定ostreolysin A(OlyA)结合,用于研究磷脂酰胆碱(PC)对鞘磷脂(SM)/胆固醇相互作用的影响
  • 作为鞘脂代谢物定量分析的标准品
  • 作为液相色谱-串联质谱(LC/MS/MS)法对表皮脂质进行绝对定量的标准品

包裝

5 mL棕色玻璃螺旋盖样品瓶(860586P-10mg)
5 mL棕色玻璃螺旋盖样品瓶(860586P-5mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Ebru Afşar et al.
Redox biology, 30, 101430-101430 (2020-01-25)
We aimed to determine sphingolipid levels and examine apoptotic pathways in human retinal pigment epithelial cells (ARPE-19) undergoing endoplasmic reticulum (ER) stress. Cells were treated with tunicamycin (TM) to induce ER stress and tauroursodeoxycholic acid (TUDCA), an ER stress inhibitor
Zhixing Wang et al.
The Journal of investigative dermatology, 133(3), 668-676 (2012-10-26)
The stratum corneum is composed of protein-enriched corneocytes embedded in an intercellular matrix of nonpolar lipids organized as lamellar layers and giving rise to epidermal permeability barrier (EPB). EPB defects have an important role in the pathophysiology of skin diseases
Delphine Milhas et al.
FEBS letters, 584(9), 1887-1894 (2009-10-28)
The plasma membrane (PM) is a major resource for production of bioactive lipids and contains a large proportion of the cellular sphingomyelin (SM) content. Consequently, the regulation of SM levels at the PM by enzymes such as sphingomyelinase (SMase) and

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