860062C

Brain SM

Avanti Research^™ - A Croda Brand

• 别名: 18:0 SM; Octadecanoyl Sphingomyelin; N-octadecanoyl-D-erythro-sphingosylphosphorylcholine; N-(octadecanoyl)-sphing-4-enine-1-phosphocholine
• CAS号: 383907-91-3
• MDL號碼: MFCD02259130
• 分類程式碼代碼: 12352211
• NACRES: NA.25

属性

• 描述: Sphingomyelin (Brain, Porcine), chloroform
• 化驗: >99% (TLC)
• 形狀: liquid
• 包裝: pkg of 1 × 2.5 mL (860062C-25mg); pkg of 2 × 4 mL (860062C-200mg)
• 製造商／商標名: Avanti Research^™ - A Croda Brand
• 濃度: 10 mg/mL (860062C-25mg); 25 mg/mL (860062C-200mg)
• 脂質類型: sphingolipids
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• SMILES 字串: [P](=O)([O-])(OC[C@H](NC(=O)CCCCCCCCCCCCCCCCC)[C@H](O)\C=C\CCCCCCCCCCCCC)OCC[N+](C)(C)C
• InChI: 1S/C41H83N2O6P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-41(45)42-39(38-49-50(46,47)48-37-36-43(3,4)5)40(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h32,34,39-40,44H,6-31,33,35-38H2,1-5H3,(H-,42,45,46,47)/b34-32+/t39-,40+/m0/s1
• InChI 密鑰: LKQLRGMMMAHREN-YJFXYUILSA-N

说明

一般說明

As a major constituent of cell membranes, sphingomyelin is found at particularly high concentrations in the membranes of nerve cells (in the myelin sheaths) and red blood cells. It was previously thought to have a purely structural role, similar to the function of phosphatidylcholine, through intermolecular interactions mediated by the 2-amide group, the 3-hydroxy group and the 4,5-trans double bond of the sphingoid base. However, it is now appreciated that sphingomyelin has a high affinity for cholesterol and that these two lipids pack tightly into liquid-ordered domains among a liquid-disordered phase to form lipid rafts. These membrane microdomains are thought to function as signaling platforms that regulate the localization and interactions of proteins. But sphingomyelin does not just influence signaling as a component of lipid rafts — it is also a precursor to ceramides and other sphingolipid metabolites that comprise the sphingomyelin cycle or sphingolipid network.
Sphingomyelin and related lipids

應用

Brain SM may be used:

• for ion-mobility spectrometry–mass spectrometry (IMS-MS)
• for lipid mixture in giant unilamellar vesicles
• as a growth medium for madin-darby canine kidney (MDCK) cells

包裝

5 mL Clear Glass Sealed Ampule (860062C-200mg)

5 mL Clear Glass Sealed Ampule (860062C-25mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全信息

• 象形圖: GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• 防範說明: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• 危險分類: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• 標靶器官: Central nervous system, Liver,Kidney
• 水污染物質分類（WGK）: WGK 3