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Merck

840034P

Avanti

16:0-18:1 PS (POPS)

Avanti Research - A Croda Brand

别名:

1-十六烷酰基-2-(9Z-十八烯酰基)-sn-甘油-3-磷酸-L-丝氨酸(钠盐);POPS; PS(16:0/18:1(9Z)); 110669

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About This Item

经验公式(希尔记法):
C40H75NO10PNa
分子量:
783.99
MDL號碼:
分類程式碼代碼:
51191904
NACRES:
NA.25

描述

1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine (sodium salt)

化驗

>99% (TLC)

形狀

powder

包裝

pkg of 1 × 10 mg (840034P-10mg)
pkg of 2 × 100 mg (840034P-200mg)
pkg of 5 × 100 mg (840034P-500mg)
pkg of 1 × 25 mg (840034P-25mg)

製造商/商標名

Avanti Research - A Croda Brand

脂質類型

phospholipids
cardiolipins

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

InChI 密鑰

RQYKXRYGZHMUSU-JEAFVVATSA-M

一般說明

磷酸丝氨酸/磷脂酰丝氨酸(PS)是一种内源性磷脂,存在于所有聚阴离子大分子中。

應用

16:0-18:1 PS (POPS) 已用于:
  • 纳米盘(nanodisc)制备用磷脂混合物
  • 脂质体制备
  • 表面等离振子体共振(SPR)分析用脂质囊泡制备

生化/生理作用

磷酸丝氨酸(PS)可用作识别癌症抗原125(CA 125)的模板。它对健康的神经细胞膜和髓磷脂至关重要。外源性PS可以被人体主动吸收。它具有穿越血脑屏障的能力。它在短期记忆形成、创造新记忆、集中注意力、推理和解决问题以及其它一些认知活动的能力中起关键作用。它积极参与运动功能,例如快速反应和反射。

包裝

5 mL透明密封玻璃安瓿瓶(840034P-10mg)
5 mL透明密封玻璃安瓿瓶(840034P-200mg)
5 mL透明密封玻璃安瓿瓶(840034P-25mg)
5 mL透明密封玻璃安瓿瓶(840034P-500mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Cellular phosphatase activity of C1-Ten/Tensin2 is controlled by Phosphatidylinositol-3, 4, 5-triphosphate binding through the C1-Ten/Tensin2 SH2 domain
Kim E, et al.
Cellular Signalling, 51, 130-138 (2018)
Fluorophore Labeling, Nanodisc Reconstitution and Single-molecule Observation of a G Protein-coupled Receptor
Lamichhane R, et al.
Bio-protocol, 7(12) (2017)
Josef Melcr et al.
Journal of chemical theory and computation, 16(1), 738-748 (2019-11-26)
Phosphatidylserine (PS) lipids are important signaling molecules and the most common negatively charged lipids in eukaryotic membranes. The signaling can be often regulated by calcium, but its interactions with PS headgroups are not fully understood. Classical molecular dynamics (MD) simulations
Carina Drechsler et al.
Biophysical journal, 115(8), 1509-1517 (2018-09-30)
Lipid asymmetries between the outer and inner leaflet of the lipid bilayer exist in nearly all biological membranes. Although living cells spend great effort to adjust and maintain these asymmetries, little is known about the biophysical phenomena within asymmetric membranes
Examination of the Interaction between a Membrane Active Peptide and Artificial Bilayers by Dual Polarisation Interferometry
Payne JAE, et al.
Bio-protocol, 7(1), e2087-e2087 (2017)

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