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化驗
98%
形狀
solid
mp
232-233 °C (lit.)
SMILES 字串
O=C(NC1CCCCC1)NC2CCCCC2
InChI
1S/C13H24N2O/c16-13(14-11-7-3-1-4-8-11)15-12-9-5-2-6-10-12/h11-12H,1-10H2,(H2,14,15,16)
InChI 密鑰
ADFXKUOMJKEIND-UHFFFAOYSA-N
基因資訊
human ... EPHX2(2053)
mouse ... Ephx2(13850)
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儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
其他客户在看
T Watanabe et al.
Analytical biochemistry, 299(2), 227-234 (2001-12-04)
A rapid and reliable electrospray tandem mass spectrometric method for soluble epoxide hydrolase (sEH) inhibitors in rat hepatic microsomes is described. Four synthesized sEH inhibitors were extracted from rat hepatic microsomes with ethyl acetate and were determined by HPLC using
Sarbani Ghosh et al.
Basic & clinical pharmacology & toxicology, 102(5), 453-458 (2008-03-04)
Cytochrome P450-derived epoxyeicosatrienoic acids (EET) are biologically active metabolites of arachidonic acid that have potent effects on renal vascular reactivity and tubular ion transport and have been implicated in the control of blood pressure. EETs are hydrolyzed to their less
Michele Aresta et al.
Dalton transactions (Cambridge, England : 2003), 39(30), 6985-6992 (2010-06-15)
NbCl(5) x (N,N'-dicyclohexylurea) 1a owns a distorted octahedral structure due to intramolecular NH...Cl bonding. The unit cell contains four units which are intermolecularly NH...Cl and NH...N bonded. An extended intramolecular network of H-bonding (N-H...Cl, CH...Cl, CH...N) causes the 3D self
Z Yu et al.
Circulation research, 87(11), 992-998 (2000-11-25)
The cytochrome P450-derived epoxyeicosatrienoic acids (EETs) have potent effects on renal vascular reactivity and tubular sodium and water transport; however, the role of these eicosanoids in the pathogenesis of hypertension is controversial. The current study examined the hydrolysis of the
Sung Hee Hwang et al.
Journal of medicinal chemistry, 50(16), 3825-3840 (2007-07-10)
A series of N,N'-disubstituted ureas having a conformationally restricted cis- or trans-1,4-cyclohexane alpha to the urea were prepared and tested as soluble epoxide hydrolase (sEH) inhibitors. This series of compounds showed low nanomolar to picomolar activities against recombinant human sEH.
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