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739979

Sigma-Aldrich

Resomer® RG 858 S，聚(D,L-丙交酯-共-乙交酯)

ester terminated, lactide:glycolide 85:15, Mw 190,000-240,000

别名:

PLGA

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About This Item

线性分子式:
[C3H4O2]x[C2H2O2]y
CAS号:
26780-50-7
分類程式碼代碼:
12162002
NACRES:
NA.23

品質等級

100

形狀

amorphous

饋電比

lactide:glycolide 85:15

分子量

Mw 190,000-240,000

降解時間

<9 months

黏度

1.3-1.7 dL/g, 0.1 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)

儲存溫度

2-8°C

InChI

1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2

InChI 密鑰

LCSKNASZPVZHEG-UHFFFAOYSA-N

相关类别

一般說明

RESOMER®聚合物是生物可吸收的脂肪族聚酯，它由一系列不同比例的丙交酯和乙交酯单体、PLA立体化学和端基官能化组成。这些丙交酯和乙交酯的生物可降解均聚物和共聚物具有多种特性，其范围从降解时间长的刚性硬质半晶体材料到降解速率更快、更软的无定形材料。

應用

Electrospun Resomer® X 206 S与来自甘蔗渣的纤维素混合，可用作组织工程中的支架。
控制释放

特點和優勢

生物活性剂的控制释放、缝合线和生物可吸收性可植入装置。

法律資訊

Evonik产品
RESOMER is a registered trademark of Evonik Rohm GmbH

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儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

从最新的版本中选择一种：

分析证书(COA)

Lot/Batch Number
BCCG7417
BCCF7604
BCCC6904
BCBV9308
BCCB3648

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RESOMER??Biodegradeable Polymers for Sutures, Medical Devices, Drug Delivery Systems and Tissue Engineering
Mader K
Material Matters, 6(3), 62-62 (2011)
Rongcai Liang et al.
International journal of pharmaceutics, 454(1), 344-353 (2013-07-23)
Peptide or protein degradation often occurs when water flows into the dosage form. The aim of this study was to investigate the effect of water on exenatide acylation in poly(lactide-co-glycolide) (PLGA) microspheres. Exenatide-loaded PLGA microspheres were incubated at different relative
Shu-Chun Chuang et al.
Parasites & vectors, 6, 34-34 (2013-02-13)
Current development efforts of subunit vaccines against Toxoplasma gondii, the etiological agent of toxoplasmosis, have been focused mainly on tachyzoite surface antigen 1 (SAG1). Since microparticles made from poly (lactide-co-glycolide) (PLG) polymers have been developed as safe, potent adjuvants or
Vanna Sanna et al.
International journal of nanomedicine, 7, 5501-5516 (2012-10-25)
Resveratrol, like other natural polyphenols, is an extremely photosensitive compound with low chemical stability, which limits the therapeutic application of its beneficial effects. The development of innovative formulation strategies, able to overcome physicochemical and pharmacokinetic limitations of this compound, may
Mani Gajendiran et al.
Colloids and surfaces. B, Biointerfaces, 104, 107-115 (2013-01-10)
A series of biodegradable low molecular weight PLGA-PEG-PLGA tri-block copolymers have been synthesized in powder form. The anti-tuberculosis drug Isoniazid (INH) loaded polymeric core-shell nanoparticles (CSNPs) have been prepared by sonication followed by water-in-oil-in-water (w/o/w) double emulsification technique. The nanoparticles
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Interest in utilizing biodegradable polymers for biomedical applications has grown since the 1960s.

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