所有图片(2)
About This Item
线性分子式:
[NH2(CH2)2NH2]:(G=4);dendri PAMAM(NH2)64
CAS号:
分子量:
14214.17
MDL號碼:
分類程式碼代碼:
12162002
NACRES:
NA.23
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描述
amino surface groups
形狀
solution
分子量
generation 4.0
特點
core type ethylenediamine core (2-carbon core)
濃度
10 wt. % in methanol
號表面基團
64
折射率
n20/D 1.348
bp
64.7 °C
密度
0.813 g/mL at 25 °C
儲存溫度
2-8°C
一般說明
PAMAM树枝状聚合物，乙二胺核，4代溶液是酰胺—胺聚合物，属于树枝状聚合物。可通过两步法的界面交互反应形成围绕乙二胺中心核的代而进行制备。它含有通过正规“支化再支化”模式组装的氮和酰胺官能团。它主要用作高容量螯合剂。
應用
PAMAM树枝状聚合物，乙二胺核，4代溶液可作为引起DNA分子构象变化的压缩剂。它可结合纤维素底物，构建可用于免疫检测的生物功能表面。它可用于MRI对比剂和二氧化硅纳米球的冷凝制备。
外觀
含有 64 个表面伯氨基
法律資訊
由 Dendritech® 公司制造
Dendritech is a registered trademark of Dendritech, Inc.
訊號詞
Danger
危險分類
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
標靶器官
Eyes
儲存類別代碼
3 - Flammable liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
51.8 °F - closed cup
閃點（°C）
11 °C - closed cup
個人防護裝備
Eyeshields, Faceshields, Gloves
其他客户在看
Dendrimer enhanced ultrafiltration. 1. Recovery of Cu (II) from aqueous solutions using PAMAM dendrimers with ethylene diamine core and terminal NH2 groups
Diallo MS, et al.
Environmental Science & Technology, 39(5), 1366-1377 (2005)
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Colloids and surfaces. B, Biointerfaces, 177, 77-93 (2019-02-04)
Peptide epitopes have been widely used to develop synthetic vaccines and immunotherapies. However, peptide epitopes may exhibit poor absorption or immunogenicity due to their low molecular weights. Conversely, fourth-generation polyamidoamine (G4-PAMAM) dendrimers are nonimmunogenic and relatively nontoxic synthetic nanoparticles that
DNA compaction induced by a cationic polymer or surfactant impact gene expression and DNA degradation
Ainalem M, et al.
PLoS ONE, 9(3), e92692-e92692 (2014)
Kobayashi, H., et al.
Magn. Reson. in Med., 50, 758-758 (2003)
Felipe Vidal et al.
Molecular pharmaceutics, 13(10), 3395-3403 (2016-08-25)
Polyamidoamine (PAMAM) dendrimers are hyperbranched macromolecules which have been described as one of the most promising drug nanocarrier systems. A key process to understand is their cellular internalization mechanism because of its direct influence on their intracellular distribution, association with
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Environmental concerns are driving the replacement of volatile organic solvents by water and aqueous mixtures. This change often creates challenges because many organic molecules show low water solubility.
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