(Pro)Renin receptor regulates potassium homeostasis through a local mechanism.

(Pro)Renin receptor regulates potassium homeostasis through a local mechanism.

American journal of physiology. Renal physiology (2016-07-22)

Chuanming Xu, Aihua Lu, Hong Wang, Hui Fang, Li Zhou, Peng Sun, Tianxin Yang

ABSTRACT

(Pro)renin receptor (PRR) is highly expressed in the distal nephron, but it has an unclear functional implication. The present study was conducted to explore a potential role of renal PRR during high K

MATERIALS

Product Number

Brand

Product Description

R8129

Sigma-Aldrich

Renin Substrate Tetradecapeptide porcine, ≥97% (HPLC)

T1426

Sigma-Aldrich

Trypsin from bovine pancreas, TPCK Treated, essentially salt-free, lyophilized powder, ≥10,000 BAEE units/mg protein

A9477

Sigma-Aldrich

Aldosterone, ≥95% (HPLC)

MAB6020

Sigma-Aldrich

Anti-Cytochrome P450 11β-Hydroxylase Antibody, clone 11B2-1A4, culture supernatant, clone 11B2-1A4, Chemicon^®

T6522

Sigma-Aldrich

Trypsin inhibitor from Glycine max (soybean), powder, BioReagent, suitable for cell culture