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Key Documents

X3627

Sigma-Aldrich

Xanthine sodium salt

suitable for cell culture, ≥99%

Synonym(s):

2,6-Dihydroxypurine

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About This Item

Empirical Formula (Hill Notation):
C5H3N4NaO2
CAS Number:
Molecular Weight:
174.09
MDL number:
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.51

biological source

synthetic (organic)

Quality Level

assay

≥99%

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

≤4% methanol

solubility

1 M NaOH: 50 mg/mL, clear to slightly hazy, colorless to light yellow

SMILES string

[Na].O=C1NC(=O)c2[nH]cnc2N1

InChI

1S/C5H4N4O2.Na.H/c10-4-2-3(7-1-6-2)8-5(11)9-4;;/h1H,(H3,6,7,8,9,10,11);;

InChI key

JAZQMXVZANZJSO-UHFFFAOYSA-N

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General description

Xanthine is commonly present in tea, coffee and cocoa. Xanthine is a nitrogenous compound present in blood and urine.

Application

Xanthine sodium salt has been used:
  • as a component in superoxide dismutase (SOD)-inhibitable ferricytochrome c reduction assay
  • as a component in selection of chimeric Modified Vaccinia virus Ankara (MVA)
  • as a substrate in the reaction mixture for xanthine oxidase assay

Biochem/physiol Actions

Xanthine possesses therapeutic properties. It acts as a mild stimulant of the central nervous system.

pictograms

Health hazard

signalword

Warning

hcodes

Hazard Classifications

STOT SE 2

target_organs

Eyes

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Modern Pharmacology with Clinical Applications, 351-351 (2004)
Uric acid-lowering effect and intestinal permeability of Kampo medicine, Hachimijiogan, Yokuininto and Goshakusan
Lee SH, et al.
European journal of integrative medicine, 20(1), 193-199 (2018)
Construction of FWPV Chimaeric MVA
Buttigieg KR and Skinner MA
Bio-protocol, 5(1), 65-80 (2015)
Rau's Respiratory Care Pharmacology - E-Book (2013)
Assays for detecting biological superoxide
Zhu H
Reactive Oxygen Species, 1(1), 65-80 (2016)

Articles

Uric acid is not a direct additive to any of the classical cell culture media. However, it is present in animal sera. Consequently, uric acid is typically present in complete serum-supplemented classical cell culture systems.

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