Propranolol hydrochloride is easily soluble in ethanol and water.
(±)-Propranolol hydrochloride has been used:
- to determine whether autonomic nervous system mediated the promotive effect on skin microcirculation in rat
- as a non-selective β- receptor blocker to reduce the arrhythmogenic events
- to study its effect on oxygen-induced retinopathy in mice
1, 5, 25, 100 g in poly bottle
Propranolol hydrochloride is a β-adrenoceptor antagonist. Its action at β2 receptor results in bronchoconstriction. Due to its lipophilic nature, propranolol can penetrate to the central nervous system and has a negative effect. It serves as a 5-HT1/5-HT2 serotonin receptor antagonist. Propranolol hydrochloride is useful as an antihypertensive drug, cardiac depressant and also in the treatment of angina pectoris. It decreases the effect of stress and exercise on heart by reducing the rate of contraction and conduction of impulse. It is known to competitively block the action of catecholamines.
Features and Benefits
This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm. This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Shelf-life of the solid is at least four years if stored protected from the uptake of moisture.