SRP8046
Netrin-1 (human): FC (human)
recombinant, expressed in HEK 293 cells, >95% (SDS-PAGE)
Synonym(s):
ACRP30headless:TNFSF13, NTN1
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About This Item
UNSPSC Code:
12352200
NACRES:
NA.32
Recommended Products
biological source
human
recombinant
expressed in HEK 293 cells
assay
>95% (SDS-PAGE)
form
lyophilized
mol wt
~90 kDa by SDS-PAGE
packaging
pkg of 10 μg
storage condition
avoid repeated freeze/thaw cycles
impurities
<0.1 EU/μg endotoxin, tested
color
white
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... NTN1(9423)
General description
Netrin-1 controls guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Netrin 1 is also Involved in tumorigenesis by regulating apoptosis.
Physical form
Lyophilized from PBS with trehalose and Brij35.
Reconstitution
Reconstitute with 100 μL deionized water.
Other Notes
Human netrin-1 (aa 25-604) is fused at the C-terminus to the Fc portion of human IgG1.
Storage Class
10 - Combustible liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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