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SML3040

Sigma-Aldrich

ZnDA-1H

≥98% (HPLC)

Synonym(s):

4-(3-(Bis(pyridin-2-ylmethyl)amino)-2-oxo-7,8-dihydro-2H-pyrano[3,2-g]quinolin-9(6H)-yl)-N-(2-(2-((6-chlorohexyl)oxy)ethoxy)ethyl)butanamide

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About This Item

Empirical Formula (Hill Notation):
C38H48ClN5O5
Molecular Weight:
690.27
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

Biochem/physiol Actions

ZnDA-1H is a highly selective fluorescent probe for Zn2+ that exhibits a reversible fluorescence response toward labile Zn2+ in various intracellular organelles, including the nucleus, mitochondria, endoplasmic reticulum, and Golgi apparatus in live cells. ZnDA-1H is not susceptible to intracellular pH variation

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Toshiyuki Kowada et al.
Cell chemical biology, 27(12), 1521-1531 (2020-10-01)
Fluorescent Zn2+ probes used for the quantitative analysis of labile Zn2+ concentration ([Zn2+]) in target organelles are crucial for understanding the role of Zn2+ in biological processes. Although several fluorescent Zn2+ probes have been developed to date, there is still

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