SML0675

α-Methylnorepinephrine

≥95% (HPLC)

• Synonym(s): α-(1-Aminoethyl)-3,4-dihydroxybenzyl alcohol, (-)-α-Methylnorepinephrine, 4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol, L-4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol, (-)-Nordefrin, (-)3,4-Dihydroxynorephedrine, Corbadrine, Levonordefrin
• Empirical Formula (Hill Notation): C₉H₁₃NO₃
• CAS Number: 829-74-3
• Molecular Weight: 183.20
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Quality Level: 100
• assay: ≥95% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to light brown
• solubility: DMSO: 5 mg/mL, clear (warmed)
• storage temp.: −20°C
• InChI: 1S/C9H13NO3/c1-5(10)9(13)6-2-3-7(11)8(12)4-6/h2-5,9,11-13H,10H2,1H3/t5-,9-/m0/s1
• InChI key: GEFQWZLICWMTKF-CDUCUWFYSA-N

Description

Biochem/physiol Actions

α-Methylnorepinephrine (αMNE) is an α2-adrenergic agonist and is useful in cardiopulmonary resuscitation (CPR) during myocardial dysfunction especially in animals. αMNE improves water absorption in the jejunum and is blood-brain barrier impermeable.

α-Methylnorepinephrine is a sympathomimetic amine and vasoconstrictor. α-Methylnorepinephrine is used clinically in dentistry in local anesthetic solutions.

Features and Benefits

This compound is featured on the α2-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302 + H312 + H332,H315,H319,H335
• pcodes: P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable