SML0309

Sodium phenylbutyrate

≥98% (HPLC)

• Synonym(s): 4-PBA, 4-Phenylbutyric acid, 4-phenylbutyrate, Buphenyl, Sodium 4-phenylbutyrate, TriButyrate
• Empirical Formula (Hill Notation): C₁₀H₁₁NaO₂
• CAS Number: 1716-12-7
• Molecular Weight: 186.18
• MDL number: MFCD00800247
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825314
• NACRES: NA.77

Properties

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: H₂O: ≥5 mg/mL
• storage temp.: room temp
• SMILES string: [Na+].[O-]C(=O)CCCc1ccccc1
• InChI: 1S/C10H12O2.Na/c11-10(12)8-4-7-9-5-2-1-3-6-9;/h1-3,5-6H,4,7-8H2,(H,11,12);/q;+1/p-1
• InChI key: VPZRWNZGLKXFOE-UHFFFAOYSA-M

Description

General description

Sodium phenylbutyrate stimulates urinary nitrogen excretion. It is a prodrug, which undergoes β-oxidation to phenylacetate. Sodium phenylbutyrate is used to treat urea cycle disorder. It might be associated with menstrual dysfunction, amenorrhea and painful mucositis of the esophagus and stomach.

Application

Sodium phenylbutyrate has been used as an endoplasmic reticulum (ER) stress inhibitor to study the role of ER stress in the expression of betatrophin.

Biochem/physiol Actions

Sodium phenylbutyrate is a histone deacetylase inhibitor.

Features and Benefits

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Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable