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Key Documents

SCP0191

Sigma-Aldrich

MMP 2 / MMP 9 Substrate

≥95% (HPLC), lyophilized

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About This Item

Empirical Formula (Hill Notation):
C44H61N13O13S1
Molecular Weight:
1012.10
UNSPSC Code:
12352200
NACRES:
NA.32

product name

MMP 2 / MMP 9 Substrate,

assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥78%

storage condition

protect from light

storage temp.

−20°C

Amino Acid Sequence

DNP-Pro-Leu-Gly-Met-Trp-Ser-Arg

Application

Matrix metalloproteinases (MMP) are a family of zinc-dependent endopeptidases that degrade matrix proteins. MMPs include collagenases, gelatinases, matrilysins, enamelysins, metalloelastases, stromelysins and other structural protein and receptor lysins. The activity of these enzymes is selectively inhibited or measured by appropriately labeled peptides. DNP-Pro-Leu-Gly-Met-Trp-Ser-Arg (DNP-PLGMWSR), Dnp-Pro-Leu-Gly-Leu-Trp-Ala-D-Arg-NH2 (DNP-PLGLWA-D-R-NH2), Dnp-Pro-Gln-Gly-Ile-Ala-Gly-Gln-D-Arg-OH (DNP-PQGIAGQ-D-R-OH) and MOCAc [(7-methoxy coumarin-4-yl) acetyl]-RPKPYANvaWMK(Dnp[2,4-dinitrophenyl])-NH(2) are substrates for matrix metalloproteinase 2 and matrix metalloproteinase 9.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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