SAB5700292

Anti-Phospho-EGFR-Y992 antibody produced in rabbit

• Synonym(s): EGFR, ERBB, ERBB1, HER1, NISBD2, PIG61, mENA
• UNSPSC Code: 12352203
• NACRES: NA.43

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 134; 44; 69; 77
• species reactivity: human, mouse
• concentration: 0.49 mg/ml
• technique(s): western blot: 1:500-1:2000
• UniProt accession no.: P00533
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pTyr992)
• Gene Information: human ... EGFR(1956)

Description

General description

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

Immunogen

A phospho specific peptide corresponding to residues surrounding Y992 of human EGFR.

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable