SAB5600114

Anti-CD140b (PDGF Receptor beta)antibody, Rabbit Monoclonal

recombinant, expressed in HEK 293 cells, clone RM303, purified immunoglobulin

• Synonym(s): Platelet-derived growth factor receptor beta
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• recombinant: expressed in HEK 293 cells
• Quality Level: 100
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: RM303, monoclonal; recombinant monoclonal
• form: buffered aqueous glycerol solution
• species reactivity: human
• technique(s): immunohistochemistry: 1:500-1:1000; western blot: 1:250-1:500
• isotype: IgG
• NCBI accession no.: 5159
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... PDGFRB(5159)

Description

General description

The PDGFRB (platelet derived growth factor receptor β) gene is mapped to human chromosome 5q32. It encodes for a receptor tyrosine kinase.

Specificity

This antibody reacts to human CD140b (PDGFR-beta) (Platelet-derived growth factor receptor beta).

Immunogen

A peptide corresponding to the C-terminus of human CD140b.

Biochem/physiol Actions

PDGFRB (platelet derived growth factor receptor β) acts as a regulator of mesenchymal cells in tumour cells. Upregulation of the gene is observed in gastric cancer, breast and prostate cancers. Mutations in the gene is associated with infantile myofibromatosis.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable