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Key Documents

SAB4301189

Sigma-Aldrich

Anti-ABCA4 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

ABCR, FFM, RMP, RP19, STGD

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

concentration

0.9 mg/mL

technique(s)

immunohistochemistry: 1:25- 1:100

isotype

IgG

accession no.

NP_000341.2

UniProt accession no.

P78363

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ABCA4(24)

Specificity

The antibody detects endogenous levels of total ABCA4 protein.

Immunogen

Synthetic peptide corresponding to a region derived from internal residues of human ATP-binding cassette, sub-family A (ABC1), member 4

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Thomas A Ray et al.
Nature communications, 11(1), 3328-3328 (2020-07-06)
Genes encoding cell-surface proteins control nervous system development and are implicated in neurological disorders. These genes produce alternative mRNA isoforms which remain poorly characterized, impeding understanding of how disease-associated mutations cause pathology. Here we introduce a strategy to define complete
Aneta Ścieżyńska et al.
International journal of molecular sciences, 21(10) (2020-05-18)
ABCA4 gene mutations are the cause of a spectrum of ABCA4 retinopathies, and the most common juvenile macular degeneration is called Stargardt disease. ABCA4 has previously been observed almost exclusively in the retina. Therefore, studying the functional consequences of ABCA4
Nicolas Taveau et al.
Experimental & molecular medicine, 52(7), 1090-1101 (2020-07-10)
Environmental light has deleterious effects on the outer retina in human retinopathies, such as ABCA4-related Stargardt's disease and dry age-related macular degeneration. These effects involve carbonyl and oxidative stress, which contribute to retinal cell death and vision loss. Here, we

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