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species reactivity
human
technique(s)
ELISA: suitable
assay range
inter-assay cv: <10%
intra-assay cv: <12%
shipped in
wet ice
storage temp.
−20°C
General description
The antibody pair provided in this kit recognizes Human Hemoglobin. Hemoglobin (Hb) is an iron-containing metalloprotein, which is highly expressed in red blood cells. In addition, it is also expressed in nonerythroid cells such as epithelial cells of different origin. Hb is a tetramer composed of two α-globin chains and two β-globin chains. α-globin and β-globin chains is encoded by a gene mapped to human chromosome 16 and 11, respectively.
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Biochem/physiol Actions
Hemoglobin (Hb) serves as the primary means of oxygen transport in vertebrates. Hb exhibits antioxidant and antimicrobial activity. Alterations in blood hemoglobin levels occur in many diseases such as anemia and polycythemia. In addition, abnormalities in Hb concentration might be implicated in pathologies associated with various respiratory diseases, such as idiopathic pulmonary fibrosis (IPF) and chronic obstructive lung disease (COPD).
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
Storage Class
8A - Combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Find documentation for the products that you have recently purchased in the Document Library.
Polycythemia vera masked due to severe iron deficiency anemia.
Kambali S and Asma T
Hematology/oncology and Stem Cell Therapy, 11(1), 38-40 (2016)
Mechanisms linking red blood cell disorders and cardiovascular diseases.
Mozos I.
BioMed Research International, 2015, 12-12 (2015)
Hemoglobin expression in nonerythroid cells: novel or ubiquitous?
Saha D, et al.
International Journal of Inflammation, 2014, 8-8 (2014)
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