R116

Riluzole

≥98% (HPLC), solid, glutamate release inhibitor

• Synonym(s): 2-Amino-6-(trifluoromethoxy)benzothiazole
• Empirical Formula (Hill Notation): C₈H₅F₃N₂OS
• CAS Number: 1744-22-5
• Molecular Weight: 234.20
• MDL number: MFCD00210213
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278006
• NACRES: NA.77

Properties

• product name: Riluzole, solid
• form: solid
• originator: Sanofi Aventis
• SMILES string: Nc1nc2ccc(OC(F)(F)F)cc2s1
• InChI: 1S/C8H5F3N2OS/c9-8(10,11)14-4-1-2-5-6(3-4)15-7(12)13-5/h1-3H,(H2,12,13)
• InChI key: FTALBRSUTCGOEG-UHFFFAOYSA-N
• Gene Information: human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335) ; rat ... Scnn1g(24768)

Description

Biochem/physiol Actions

Glutamate release inhibitor; anticonvulsant

Features and Benefits

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H300
• pcodes: P301 + P310 + P330
• Hazard Classifications: Acute Tox. 2 Oral
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges