P1132

Pterine

~95%

• Synonym(s): 2-Amino-4-hydroxypteridine, 2-Amino-4-oxodihydropteridine
• Empirical Formula (Hill Notation): C₆H₅N₅O
• CAS Number: 2236-60-4
• Molecular Weight: 163.14
• Beilstein/REAXYS Number: 150294
• EC Number: 218-799-1
• MDL number: MFCD00010557
• UNSPSC Code: 12352202
• PubChem Substance ID: 24898158
• NACRES: NA.77

Properties

• biological source: synthetic
• assay: ~95%
• form: powder
• storage temp.: 2-8°C
• SMILES string: Nc1nc(O)c2nccnc2n1
• InChI: 1S/C6H5N5O/c7-6-10-4-3(5(12)11-6)8-1-2-9-4/h1-2H,(H3,7,9,10,11,12)
• InChI key: HNXQXTQTPAJEJL-UHFFFAOYSA-N

Description

Application

Pterine has been used:

• in photochemicals assay for inducing DNA damage
• as a substrate in xanthine oxidase assay
• as a standard in thin layer chromatography (TLC) for quantifying pterine from microbes

Biochem/physiol Actions

Pterine consists of pyrazine and pyrimidine with substitutions in keto and amino group. Pterine is present in all organisms including cyanobacteria. It acts as a cofactor for redox enzymes and serves as a precursor for folic acid synthesis. Pterine from the butterfly wings absorb light and elicit incoherent scattering. Pterine induces alterations in DNA by hydroxylation of deoxyguanosine.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves