MAK553
Fluorimetric cADP-Ribose Assay Kit
sufficient for 100 fluorometric tests
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About This Item
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detection method
fluorometric
relevant disease(s)
genitourinary disorders; neurological disorders; cardiovascular diseases; cancer
shipped in
dry ice
storage temp.
−20°C
Related Categories
General description
cADP-ribose (cADPR) is a novel Ca2+ messenger derived from NAD+. ADP-riboxyl cyclase (ADPRC) catalyzes the synthesis of cADPR from NAD+, but the reaction can be reversed in the presence of high concentration of nicotinamide, producing NAD+ from cADPR stoichiometrically. The resultant NAD+ can be detected by the NAD probe. This makes monitoring cADPR in tissues and cell cultures possible in the low nM range. The NAD+ detection using NAD probe is specific to NAD+ and has no reaction to NADH. This assay can be performed in a convenient 96-well or 384-well microplate.
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
10 - Combustible liquids
wgk_germany
WGK 3
Certificates of Analysis (COA)
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