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M9035

Sigma-Aldrich

IgG1, Kappa from murine myeloma

clone MOPC 31C, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Mouse IgG1-κ

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About This Item

MDL number:
MFCD00164798
UNSPSC Code:
12352203
NACRES:
NA.46

biological source

mouse

Quality Level

200

conjugate

unconjugated

antibody form

purified immunoglobulin

clone

MOPC 31C, monoclonal

assay

≥95% (gel filtration, HPLC)

form

buffered aqueous solution

concentration

≥1 mg/mL

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

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General description

Immunoglobulins (Igs) belongs to the immunoglobulin super-family. IgG is the abundant immunoglobulin in human serum. The four classes of IgG can be IgG1, IgG2, IgG3 and IgG4.
Mammalian immunoglobins contain either lambda or kappa light chains.

Specificity

Specificity is determined by mouse monoclonal isotyping strips. The purified immunoglobulin preparation is non-reactive with mouse IgA, IgM, IgG2a, IgG2b, or IgG3.

Application

IgG1, Kappa from murine myeloma has been used in:
  • chromatin immunoprecipitation (ChIP)
  • immunofluorescence
  • immunocapture
  • enzyme immunoassay
  • immunohistochemistry

Biochem/physiol Actions

IgG1 is the most abundant and its deficiency results in hypogammaglobulinemia. IgG antibody have enormous therapeutic potential and the Fc region is involved the development of therapeutic antibody.

Physical form

Solution in 0.02 M Tris buffered saline, pH 8.0, containing 0.02% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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