M2537
Mevastatin
≥98% (HPLC), powder or crystals
Synonym(s):
Compactin, ML-236B
About This Item
Quality Level
assay
≥98% (HPLC)
form
powder or crystals
color
white to light yellow
mp
151 °C
solubility
ethanol: 25-26 mg/mL, clear, colorless
antibiotic activity spectrum
neoplastics
mode of action
enzyme | inhibits
originator
Daiichi-Sankyo
storage temp.
2-8°C
SMILES string
[H][C@]12[C@H](CCC=C1C=C[C@H](C)[C@@H]2CC[C@@H]3C[C@@H](O)CC(=O)O3)OC(=O)[C@@H](C)CC
InChI
1S/C23H34O5/c1-4-14(2)23(26)28-20-7-5-6-16-9-8-15(3)19(22(16)20)11-10-18-12-17(24)13-21(25)27-18/h6,8-9,14-15,17-20,22,24H,4-5,7,10-13H2,1-3H3/t14-,15-,17+,18+,19-,20-,22-/m0/s1
InChI key
AJLFOPYRIVGYMJ-INTXDZFKSA-N
Gene Information
human ... HMGCL(3155) , HMGCR(3156)
rat ... Hmgcr(25675)
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General description
Application
- to analyze its effects on chronic lymphocytic leukemia (CLL) cells by cytotoxic assay
- as a prenylation inhibitor to analyze its effects on human embryonic kidney (HEK) cells transfected with K-Ras
- as a statin agent to study its anti-cancer effect on human breast cancer cells and glioblastoma in vitro
Biochem/physiol Actions
Features and Benefits
Packaging
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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