HMGCL
3-hydroxymethyl-3-methylglutaryl-CoA lyase
Synonyms:
HL
Species:
Human HMGCL (3155), Mouse Hmgcl (15356), Rat Hmgcl (79238), Zebrafish hmgcl (394190), chicken HMGCL (396316), dog HMGCL (478187), domestic cat HMGCL (101099569), cow HMGCL (317658), domestic guinea pig Hmgcl (100713291), naked mole-rat Hmgcl (101716848)
UniProtKB ID:
Gene ID:
- Human(3155) Summary: The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
- Mouse(15356) 3-hydroxy-3-methylglutaryl-Coenzyme A lyase
- Rat(79238) 3-hydroxymethyl-3-methylglutaryl-CoA lyase
- Zebrafish(394190) 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (hydroxymethylglutaricaciduria)
- chicken(396316) 3-hydroxymethyl-3-methylglutaryl-CoA lyase
- dog(478187) 3-hydroxymethyl-3-methylglutaryl-CoA lyase
- domestic cat(101099569) 3-hydroxymethyl-3-methylglutaryl-CoA lyase
- cow(317658) 3-hydroxymethyl-3-methylglutaryl-CoA lyase
- domestic guinea pig(100713291) 3-hydroxymethyl-3-methylglutaryl-CoA lyase
- naked mole-rat(101716848) 3-hydroxymethyl-3-methylglutaryl-CoA lyase
- sheep(101119699) 3-hydroxymethyl-3-methylglutaryl-CoA lyase
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-HMGCL antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-HMGCL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
esiRNA
Product Number
Description
Species